The main aim of this study is to investigate if patients that received an ankle arthrodesis, have arthritis in the adjacent joints (subtalar joint and talonavicular joint). Furthermore, we would like to study (1) the amount of increase of arthritis…
ID
Source
Brief title
Condition
- Joint disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study outcome is the degree of arthritis in the subtalar joint and
talonavicular joint, scored with the Kellgren and Lawrence score based on a
CAT-scan.
Secondary outcome
Degree of increase of arthritis in the adjacent joints between pre-operative
CAT-scan and follow-up CAT scan.
Degree of arthritis in in adjacent joint in the ankle with the ankle
arthrodesis compared to the contralateral ankle
Correlation between patient reported outcomes and degree of arthritis of the
adjacent joints.
Background summary
In patients with end-stage ankle arthritis, an ankle arthrodesis is a common
surgical procedure for pain relievement. Due to changed biomechanical loading
after an ankle arthrodesis, patients might be at increased risk of adjacent
joint degeneration. Several studies showed, that patients with an ankle
arthrodesis do have arthritis in the adjacent joints. However, most of those
studies do not report preoperative arthritis grade. Therefore, it remains
unclear if arthritis of the adjacent joints is a consequence of the arthrodesis
or if it was already existing before the arthrodesis. Only few studies compared
the amount of arthritis before the arthrodesis to the amount of arthritis after
the arthrodesis. Interestingly, those studies reported that in most patients
with adjacent joint arthritis, the arthritis was already pre-existing before
the ankle arthrodesis. Hendrickx et al. 2011 reported that progression of
osteoarthritis in adjacent joint is likely after an ankle arthrodesis, but that
it becomes rarely symptomatic. Overall, as has been described in the review of
Ling et al., a paucity of studies evaluate the preoperative prevalence of
adjacent joint arthritis and therefore it is still unclear if an ankle
arthrodesis increases the risk of adjacent joint arthritis.
Study objective
The main aim of this study is to investigate if patients that received an ankle
arthrodesis, have arthritis in the adjacent joints (subtalar joint and
talonavicular joint). Furthermore, we would like to study (1) the amount of
increase of arthritis in the adjacent joints compared to before surgery, (2)
the degree of arthritis in the contralateral ankle, (3) the correlation between
degree of arthritis and patient reported outcomes.
Study design
Observational study
Study burden and risks
Patients will visit the outpatient clinic of the department of Orthopaedics of
the Erasmus MC for a bilateral CAT-scan, x-rays, physical examination of the
ankle and to fill in questionnaires. This will take approximately 1 hour. These
are all standard clinical scans and test, and patients will not be exposed to
any risks.
's-Gravendijkwal 230
Rotterdam 3015CE
NL
's-Gravendijkwal 230
Rotterdam 3015CE
NL
Listed location countries
Age
Inclusion criteria
Patient has had ankle arthrodesis in the Erasmus MC at the department or orthopedics between 2004 and 2017, a pre-operatieve CAT-scan is available
Exclusion criteria
- Received a double or triple arthrodesis
- Arthrodesis with an intramedullary nail or external fixator
- Amputation of the ankle after the arthrodesis
- Patient deceased
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL65370.078.18 |
| OMON | NL-OMON23848 |