The objectives of our study are 1) to estimate the prevalence of LJM in patients with diabetes type 2 in The Netherlands, with a special focus on the shoulder.2) to better understand the role of diabetic neuropathy in the development of shoulder…
ID
Source
Brief title
Condition
- Diabetic complications
- Musculoskeletal and connective tissue disorders NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. The prevalence of upper extremity Limited Joint Mobility in patients with
type 2 diabetes;
2. The prevalence of specific shoulder disorders in type 2 diabetes patients
with shoulder pain;
3. The presence of muscle denervation, as a sign of diabetic neuropathy, in
type 2 diabetes patients with shoulder pain.
Secondary outcome
The association between muscle denervation and shoulder disorders in patients
with and without type 2 diabetes
Background summary
Diabetes is common in the Netherlands, and also shoulder and hand disorders are
frequently seen in Dutch general practice. Despite the fact that several
international studies concluded that examination of the hand and shoulder
should be included in diabetic patients* periodic checks, screening for limited
joint mobility (LJM) is not incorporated in the guidelines. Given the
relationship between the duration of hyperglycaemia and LJM, the question
arises whether LJM is also prevalent in the Dutch diabetes population. If LJM
is prevalent, early diagnosis and treatment can reduce pain and functional
limitations, allowing for a better control of normal daily activities,
self-management and quality of life. Furthermore, the exact pathophysiology of
shoulder disorders in diabetes patients remains uncertain, but there is
evidence that the shoulder can be affected through two pathophysiological
pathways: connective tissue damage and neuropathy. New, in-depth knowledge is
needed in order to prevent the development of chronic shoulder pain.
Study objective
The objectives of our study are
1) to estimate the prevalence of LJM in patients with diabetes type 2 in The
Netherlands, with a special focus on the shoulder.
2) to better understand the role of diabetic neuropathy in the development of
shoulder disorders.
Study design
Observational cross sectional study composed of two phases; the first phase is
descriptive and the second phase is analytic.
Study burden and risks
Filling in the questionnaire in phase 1 takes approximately 10-15 minutes. No
risks are associated.
In phase 2 the participants spend 30-60 minutes in the research centre (Meditta
Medical Centre); the participants undergo a physical examination and ultrasound
scanning of the shoulder. All these test are non-invasive and no risks are
known. Healthy participants will be examined at their department; this takes 15
minutes.
Debyeplein 1
Maastricht 6229 HA
NL
Debyeplein 1
Maastricht 6229 HA
NL
Listed location countries
Age
Inclusion criteria
Phase 1
- Type 2 diabetes
- men and women aged 30-70 year
Phase 2
- Subjects with shoulder pain for at least four weeks
- Matched patients (non-diabetic) with shoulder pain
Exclusion criteria
Inability to fill out the questionnaire or sign the informed consent
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL63328.096.17 |