Correlation between the MET-REPAIR questionnaire and the six-minute walk test

Adverse cardiac events are an important complication of noncardiac surgery.A
core component to estimate the perioperative cardiac risk is an estimation of
the cardiovascular functional capacity expressed as metabolic equivalents
(METs). Cardiopulmonary exercise testing provides a good objective measure of
the MET score, which in turn is a strong predictor of postoperative outcome.
However, for practical reasons METs are usually estimated by self-reported
functional capacity. However, in contrast to measured METs, the evidence on
estimated METs and outcome after noncardiac surgery is limited and not
conclusive.
Therefore, a prospective cohort study is initiated by the European Society of
Anesthesiology to study the predictive value of the MET score as estimated by a
questionnaire on major adverse cardiovascular events or cardiovascular
mortality (MET REPAIR study, NCT03016936).
Regarding this questionnaire, it is important to study to which extent the
estimated MET score correlates to the actual measured functional capacity.

The primary objective is to determine to which extent the MET score as
estimated by the MET-REPAIR questionnaire correlates to the physical capacity
level as measured by the 6MWT.
The secondary objective is to determine to which extent the following items
from the MET REPAIR questionnaire correlate with the 6MWT:
- Self-reported number of floors that can be climbed without having to stop to
rest
- Self-reported rating of cardiorespiratory fitness as compared to the
patients* peers
- Self-reported daily/weekly physical activity.

Prospective cohort study

The burden of participation consist of the 6-minute walk test. The risk of this
6 minute walk test is considered minimal. Although there is no direct benefit
for individual participants, the potential benefit for assessing perioperative
cardiac risk in non-cardiac surgery for future patients is considerable.