The primary objectives of this study are:1. To assess the amount of physical activity of acutely hospitalized elderly *70 years during hospitalization and to create reference values regarding the amount of time patients are standing and walking per…
ID
Source
Brief title
Condition
- Other condition
- Age related factors
Synonym
Health condition
geriatric disorders
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
In order to create reference values regarding the amount of time patients are
standing and walking per day): mean number of minutes spent physically active
(standing and walking) per day (defined as the total number of minutes standing
and walking divided by the total number of valid measurement days in the period
between inclusion and (intended) discharge).
In order to create a prediction model, this will be dichotomized into a low and
high amount of time spent physically active per day during hospitalization. As
the estimated event rate of a high amount of time spent physically active per
day during hospitalization is 50%, the cut-off value between a low and high
amount of time spent physically active will be defined by dividing the cohort
at the median.
In order to create reference values regarding the number of breaks in sedentary
time per day: mean number of breaks in sedentary time (BST) per day (defined as
the total number of BST divided by the total number of valid measurement days
in the period between inclusion and (intended) discharge). A BST is defined as
any transition from being sedentary (lying or sitting) to being physically
active (standing or walking).
In order to create a prediction model, this will be dichotomized into a low and
high number of breaks in sedentary time per day during hospitalization. As the
estimated event rate of a high number of breaks in sedentary time per day
during hospitalization is 50%, the cut-off value between a low and high number
of breaks in sedentary time will be defined by dividing the cohort at the
median.
Secondary outcome
The secondary study parameters are:
-SPPB score (summary and component scores)
-AM-PAC Inpatient Basic Mobility short form score
-Age (Categories 70-79, 80-89, *90 years)
-Sex (Male / Female)
-Disability in activities of daily living (ADLs) two weeks prior to admission
(Number of disabilities on the Katz Index of Independence in Activities of
Daily Living (Katz ADL)
-The use of ambulation assistive devices prior to admission (Yes/No. If yes,
specify type of walking aid)
-Clinical diagnosis
-Physiotherapy consulted during hospitalization (Yes/No)
Background summary
Despite numerous studies supporting adverse outcomes associated with low
physical activity (PA), there is insufficient insight in the amount of PA of
acutely hospitalized Dutch elderly * 70 years. PA can be objectively measured
by accelerometers, but it is time consuming and expensive to provide every
patient with an accelerometer. We need to be able to predict which elderly
patients are likely to spend low amounts of physical activity during
hospitalization. Because of the association between PA and functional decline
it is expected that functional assessment tests like the Short Physical
Performance Battery (SPPB) or Activity Measure for Post-Acute Care (AM-PAC) can
predict the amount of PA of patients during hospitalization. Since age, sex,
clinical diagnosis, disability in ADLs 2 weeks prior to admission, the use of
ambulation assistive devices and physiotherapy consulted are also associated
with the amount of physical activity during hospitalization, these factors will
also be taken into account when predicting the probability of low amounts of
physical activity during hospitalization for acutely hospitalized elderly * 70
years.
Study objective
The primary objectives of this study are:
1. To assess the amount of physical activity of acutely hospitalized elderly
*70 years during hospitalization and to create reference values regarding the
amount of time patients are standing and walking per day and the number of
breaks in sedentary time (BST) per day, both overall and stratified by sex and
age category.
Research question: How much physical activity do acutely hospitalized elderly
*70 years get during hospitalization, both overall and stratified by sex and
age category?
2. To develop and internally validate a prediction model that can be applied as
a tool to predict the probability of a low amount of time spent physically
active during hospitalization for acutely hospitalized elderly *70 years. (The
amount of time patients are standing and walking per day during hospitalization
will be dichotomized into a low and high amount of time spent physically
active, defined by dividing the cohort at the median.)
Research questions: In addition to functional assessment tests (SPPB or
AM-PAC), which other patient characteristics can predict the probability of a
low amount of time spent physically active during hospitalization for acutely
hospitalized elderly *70 years? How well does a multivariable prediction model
including all relevant predictors discriminate between patients qualified as
spending a low amount of time physically active during hospitalization and
patients qualified as spending a high amount of time physically active during
hospitalization, and how well is that model calibrated?
3. To develop and internally validate a prediction model that can be applied as
a tool to
predict the probability of a low number of breaks in sedentary time during
hospitalization for acutely hospitalized elderly *70 years. (The number of
breaks in sedentary time per day during hospitalization will be dichotomized
into a low and high number of breaks, defined by dividing the cohort at the
median.)
Research questions: In addition to functional assessment tests (SPPB or
AM-PAC), which other patient characteristics can predict the probability of a
low number of breaks in sedentary time during hospitalization for acutely
hospitalized elderly *70 years? How well does a multivariable prediction model
including all relevant predictors discriminate between patients qualified as
performing a low number of breaks in sedentary time during hospitalization and
patients qualified as performing a high number of breaks in sedentary time
during hospitalization, and how well is that model calibrated?
Study design
This is a single center, observational, prospective cohort study.
Study burden and risks
The burden and risks on patients are minimal. Wearing a small accelerometer
should not be a burden to patients. Patients are informed that they are allowed
to take it off when they are bothered by it in any way. The SPPB and AM-PAC are
suitable to use in the geriatric hospitalized population and are performed
under supervision of a trained researcher. Patients are allowed enough time in
between scoring items to ensure that the tests are not perceived as too
strenuous. No invasive interventions will take place. The additional burden
placed on patients will be 30 minutes in which physical activity monitoring is
started and a functional assessment takes place.
P. Debeyelaan 25
Maastricht 6229 HX
NL
P. Debeyelaan 25
Maastricht 6229 HX
NL
Listed location countries
Age
Inclusion criteria
Patients aged *70 years that are acutely hospitalized in MUMC+ in the department of Internal and Geriatric Medicine.
Inclusion criteria:
-70 years or older
-Acutely hospitalized in Maastricht University Medical Centre (MUMC+) in the department of internal and geriatric medicine
-Sufficient understanding of the Dutch language
-Living at home before hospitalization
-Able to walk independently 2 weeks before admission, as scored on the Functional Ambulation Categories (FAC >3)
Exclusion criteria
-A life expectancy of less than three months as assessed by the attending physician
-Incapacitated subjects
-The inability to follow instructions due to cognitive problems or severe agitation
-A contraindication to wearing an accelerometer, fixated by a hypoallergenic plaster, on the upper leg (such as active bilateral upper leg infection, severe edema or bilateral transfemoral amputation)
-(Re)admittance to the intensive care unit
-Presence of contraindications to walking as assessed by the attending physician
-Previous participation to this study
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL65097.068.18 |