The aim of this study is to evaluate logistic challenges in including and treating donors in a prehabilitation programme.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
zijn gezonde donoren en hebben geen aandoening
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Logistic challenges in including and treating donors in a prehabilitation
programme
Secondary outcome
Measuring fatigue symptoms after live kidney donation in terms of quality of
life questionnaires (SF-36 ACUTE VERSION, MVI-20). Outcome in terms of aerobic
capacity (VO2 Max), anaerobic capacity (Wpeak), monitoring physical activity,
intramuscular glycogen turnover, postoperative complications (wound infection,
re-admissions to hospital, lung infection, bladder infection) and return to
work.
Background summary
Kidney donors are healthy individuals who donate their kidney to patients with
end-stage renal disease. Fatigue after kidney donation is a common complaint
that affects the quality of life after kidney donation and delayed return to
daily practice. A recent systematic review shows that the quality of life only
returns to baseline or was slightly reduced at 3 to 12 months after donation,
particularly for fatigue. A surgical procedure is a stress factor for patients
and the impact on their physical condition can reduce quality of life. The
physical condition of a patient is a predictive factor for postoperative
outcomes. Improving the physical activity of the donor prior to surgery by
means of a prehabilitation programme may lead to improve physical condition
during surgery and faster recovery postoperatively.
Study objective
The aim of this study is to evaluate logistic challenges in including and
treating donors in a prehabilitation programme.
Study design
In this pilot study, we will include 10 healthy people (>18 years) who are
listed to undergo a live donor nephrectomy at the Erasmus Medical Center.
Intervention
supervised SIT training twice a week for a minimum of 6 weeks prior to donation
Intervention
Sprint Interval Training (SIT)
The SIT intervention that the subjects will undergo is a sprint test on a
specific bike (High Octane Ride Bike by Matrix). This sprint test consists of 3
minutes of unloaded pedaling (30 rpm) followed by a set time of 20 seconds
pedaling at a maximum speed against a constant resistance equivalent to 4-7.5%
of bodyweight. This will be done twice with 3 minutes of unloaded pedaling (30
rpm) after each sprint. The total SIT workout will be 9 minutes and 40 seconds;
with netto intervention of 40sec all out sprint.
Study burden and risks
Several standardized questionnaires are asked to be filled in before, during
and after the SIT in order to measure fatigue and quality of life. The
questionnaires take 2-10 minutes to complete. No serious side effects are
expected the prehabilitation program.
's-Gravendijkwal 230
Rotterdam 3015CE
NL
's-Gravendijkwal 230
Rotterdam 3015CE
NL
Listed location countries
Age
Inclusion criteria
- Eligible live kidney donor
- Age above 18 years
- Meet American College of Sports Medicine (ACSM) guidelines for basic physical activity levels
- Minimum of 6 weeks prior to donation
- Written informed consent
Exclusion criteria
- Unable to read, write and understand Dutch language
- Preoperatively physical disabilities (e.g. sport injuries)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL62977.078.17 |