This study will provide reference values for the (relative) aerobic load of daily activities for people after stroke. Furthermore, it will assess the impact of relative aerobic load on daily life activity levels for people after stroke.
ID
Source
Brief title
Condition
- Other condition
- Central nervous system vascular disorders
Synonym
Health condition
cerebrovasculair accident
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
This study will assess the absolute and relative aerobic load of various daily
activities for people that have experienced a stroke. For this purpose, oxygen
consumption will be measured during these activities and during a maximal
cardiopulmonary exercise test. Furthermore, activity levels in daily life will
be assessed through activity monitoring and the relationship between activity
level, fatigue and relative aerobic load will be determined.
Secondary outcome
The aerobic load of daily tasks will additionally be expressed in heart rate
and rating of perceived exertion. Furthermore the influence of cognitive and
functional characteristics on aerobic load and on activity level will be
assessed.
Background summary
People after stroke often have a lower aerobic capacity than their able-bodied
peers. On top of that, the aerobic load of daily activities appears to be
higher in this patient group. Often, these issues are investigated separately,
but the actual impact on daily functioning can only be perceived when they are
considered jointly. Currently, reference values on aerobic load of daily
activities for people after stroke are not available. Furthermore, the
relationship between aerobic load and aerobic capacity; the relative aerobic
load, has not been quantified. It can be expected that people with a high
(predicted) relative aerobic load of daily activities will either experience
more fatigue in daily life or be less active. This fatigue or inactivity can
have a large impact on daily life and participation in the community.
Study objective
This study will provide reference values for the (relative) aerobic load of
daily activities for people after stroke. Furthermore, it will assess the
impact of relative aerobic load on daily life activity levels for people after
stroke.
Study design
This study consists of a cross-sectional study assessing the (relative) aerobic
load of different types of daily activities. A second observational study will
assess the relationship between predicted relative load of daily activities and
activity levels and experienced fatigue in daily life.
Study burden and risks
Participants in the first experiment will perform various activities of daily
life on a maximum of two days, each visit lasting a maximum of 2.5 hours.
During these activities oxygen uptake will be measured by means of breath by
breath respirometry using a mobile device. Able-bodied control subjects will
perform a cardiopulmonary exercise test (CPET) prior to the daily activity
measurements. Stroke subjects will perform a CPET as part of clinical practice
prior to participation. On the first of these visits, they will fill in
questionnaires on their functional status and participation. Participants in
the second experiment will be instructed to wear an activity monitor during
five consecutive days. The instruction visit lasts approximately 1 hour.
Relweg 51
Wijk aan Zee 1949 EC
NL
Relweg 51
Wijk aan Zee 1949 EC
NL
Listed location countries
Age
Inclusion criteria
- Is over 18 years old.
- Meets the American College of Sports Medicine (ACSM) inclusion criteria for maximal exercise testing (Thompson et al. 2013; Pescatello et al. 2014);Only applicable for people after stroke:
- Suffered a first or recurrent stroke, as diagnosed by a neurologist
- Receives rehabilitation treatment care in Heliomare
- Time since stroke between 7 days and 6 months at time of inclusion (subacute stroke; Bernhardt et al. 2017)
- Scheduled for a CPET as part of clinical practice
- Functional Ambulation Category (FAC) 2 or higher, indicating that the patient is able to perform balancing and coordinating tasks with or without some assistance
- For ambulatory activities; Berg Balance Score > 45 to limit fall risk during the activity (Berg et al. 1989)
- Able to understand instructions
Exclusion criteria
- Exclusion criteria for CPET as determined by the ACSM (Pescatello et al. 2014)
- Absolute contra-indications for exercise as determined by the ACSM (Pescatello et al. 2014)
- Cognitive or communicative disorders leading to inability to understand instructions or exercises
- Non-stroke related sensory, motoric or orthopaedic disorders influencing movements of daily living
- Non-stroke related disorders that influence aerobic load or aerobic capacity
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL64431.029.18 |