To study the effect of the availability of a predictive uveitis model in the clinical setting on the 1 year visual outcome of patients.
ID
Source
Brief title
Condition
- Ocular infections, irritations and inflammations
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Best corrected visual acuity.
Secondary outcome
Duration and dose immunosuppressives.
See Ch. 8 of the protocol.
Background summary
Uveitis is a potentially sight threatening eye disease. There are no clear
guidelines or studies directing therapy. Based on cohort studies regarding
outcome in subentities of uveitis and clinical experience, therapeutic
decisions are made on an ad hoc basis during, and adapted to, the course of the
invidual eye*s uveitis. A predictive model has been built and internally
validated using cohort and individual disease activity and therapy to predict
the resulting visual outcome.
Study objective
To study the effect of the availability of a predictive uveitis model in the
clinical setting on the 1 year visual outcome of patients.
Study design
Non-randomised, controlled trial.
Study group 1: historical cohort, group 2: use of the predictive model.
Intervention
Introduction of information of a predictive model.
Study burden and risks
Participants are not subjected to any additional time/burden or risk.
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Listed location countries
Age
Inclusion criteria
- Non-infectious uveitis.
- Age >= 18 years.
- Informed consent.
Exclusion criteria
- Major eye condition preventing any VA improvement or reduction (such as end stage glaucoma, end stage corneal diseases, end stage macular degeneration).
- Suspected or proven infectious uveitis.
- Masquerade syndromes (such as intraocular B cell lymphoma).
- Patients for whom all data of the first year since onset of their uveitis are missing.
- Patients for whom, since onset of their uveitis, data (> 3 years) are missing.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL63970.078.17 |