To examine whether there is a systematic presence of EWS and change in daily life experiences preceding transitions towards improvement of depressive symptoms within single individuals who receive psychological treatment
ID
Source
Brief title
Condition
- Mood disorders and disturbances NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter is a within-person critical transition towards
improvement of depressive symptoms.
Secondary outcome
Secundary study parameters include daily exeperiences (affect, behavior,
cognitive factors, context), heart rate variability, and physical activity over
the flow of daily life.
Background summary
A better understanding of the mechanisms at play in the process of recovery
from depression is needed to optimize the effectiveness of current treatments
for depression and to prevent depressive relapse. We propose that the change
process towards improvement of depressive symptoms may behave like a complex
dynamical system, in which sudden symptom gains can occur (i.e., sudden
transitions towards no/mild symptoms) that are preceded by early warning
signals (EWS) and change in daily life experiences that mark the first steps
towards symptom improvement. Only if we find that certain daily life
experiences or EWS temporally and systematically increase just before the jump
towards improvement within single individuals, then we know which changes in
daily life experiences and the hypothesized EWS can signal, what we can call,
*readiness for change*.
Study objective
To examine whether there is a systematic presence of EWS and change in daily
life experiences preceding transitions towards improvement of depressive
symptoms within single individuals who receive psychological treatment
Study design
The study concerns an observational study in which a repeated single-subject
intensive time-series design is adopted.
Study burden and risks
There are no risks involved in study participation. The burden associated with
participation consists of: baseline assessments (max 2 hours), a baseline
interiew (max 2 hours), filling in diary questions on a smartphone (2 minutes,
5 times a day for 4 months), conducting Heart Rate Variability (HRV)
measurements (5 minutes, 2 times a day for 4 months), wearing an accelerometer
on their wrist (4 months), carrying an extra smartphone for the HRV
measurements (only for those participants without an iOS smartphone),
completing a weekly depressive symptom scale once a week (5 minutes a week for
6 months), an evaluation interview (1,5 hour), and completing a monthly
depressive symptom scale once a month (5 minutes a month for 6 months).
Hanzeplein 1
Groningen 9713 GZ
NL
Hanzeplein 1
Groningen 9713 GZ
NL
Listed location countries
Age
Inclusion criteria
- age >= 18
-presence of depressive symptoms (Inventory of Depressive Symptomatology score >= 14)
- being bound to receive a psychological treatment for depressive symptoms
- capable of following the study procedures
- willing to and capable of giving informed consent
Exclusion criteria
- presence of a current manic episode or current psychotic symptoms
- chronic depressive symptoms (> 2 year)
- reported primary diagnosis of a personality disorder
- insufficient Dutch language skills to understand the diary questions
- inability to work with a smartphone
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL58848.042.16 |