The aim of current study is to determine reproducibility (both interscan and interreader reproducibility) of the different functional MR measurements of the kidneys.
ID
Source
Brief title
Condition
- Other condition
- Renal disorders (excl nephropathies)
Synonym
Health condition
Hypertensie
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The coefficient of variation (CV in %) , the repeatability coefficient (RC),
and a measure for reliability, the intraclass correlation coefficient (ICC)
will be calculated.
Secondary outcome
NA
Background summary
Blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) is a
method to measure renal oxygenation and quantify ischemic areas within the
kidneys. Dynamic contrast enhanced MRI (DCE-MRI) and arterial spin labeling
(ASL) can be used in the evaluation of renal blood flow.
Study objective
The aim of current study is to determine reproducibility (both interscan and
interreader reproducibility) of the different functional MR measurements of the
kidneys.
Study design
The current study is a validation study to determine interscan and interreader
reproducibility of functional MR measurements (BOLD-MRI, DCE-MRI and ASL) of
the kidney in healthy subjects. Thirty healthy subjects will be included in
this present study.
Study burden and risks
Subject will not benefit from the study. The risks associated with the
procedures performed for the study are very limited.
Heidelberglaan 100
Utrecht 3584 CX
NL
Heidelberglaan 100
Utrecht 3584 CX
NL
Listed location countries
Age
Inclusion criteria
1.Individual is >=40 years of age
Exclusion criteria
1. Known kidney or cariodvascular disease
2. Any contraindications for MRI
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL45144.041.13 |