The main goal of this project is to develop and validate a practical method to quantify slow vision. We will develop new tools to measure *perception time* during the assessment of visual acuity.
ID
Source
Brief title
Condition
- Vision disorders
- Neurological disorders of the eye
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main parameter is the outcome of the new speed acuity tests (i.e.
percentage correct answers and reaction times for the different sizes of
optotypes, accumulated in a visual acuity and delay score).
Secondary outcome
Additional parameters are the eye movement recordings (e.g., the number of
saccades needed to fixate the target, fixation stability, and saccade
properties such as amplitude-duration-velocity relationships), the results of
the Developmental Eye Movement test (DEM) and Useful Field of View (UFOV) and
the results of the funduspicture and OCT (for the group with an apparent delay,
or if already available).
Background summary
For the majority of tasks in daily life we rely on visual information; the
demands on our visual system become even greater in dynamic situations, for
example in traffic, where visual information changes rapidly over time. Most
of young adults and children are able to deal with this information
efficiently. However, if it takes too long to process and respond to visual
stimuli, problems occur. Existing tests of visual acuity do not take into
account the time that is needed to respond. In the Netherlands, people who seek
help because they encounter problems of slow vision cannot receive assistance
from institutes for the visually impaired or (visual) rehabilitation
facilities, because rehabilitation criteria are based on visual acuity but not
on the processing speed of visual stimuli. At present, the definition of visual
impairment is primarily based on distant visual acuity and visual field. There
are no nationally or internationally accepted tests to measure reaction time in
acuity testing. Nevertheless, many children and adults, both normally sighted
as visually impaired, complain about problems in coping with various daily
activities due to slow vision. For example, children need more time to complete
exercises at school, and adults as well as children encounter problems when
using digitized information (e.g. using computers) or with participation in
traffic.
Study objective
The main goal of this project is to develop and validate a practical method to
quantify slow vision. We will develop new tools to measure *perception time*
during the assessment of visual acuity.
Study design
The design of the study is an observational, cross sectional study.
Study burden and risks
The burden will consist of a maximum of two sessions of one hour per
participant. Both the traditional screening of visual functioning as the
measurements of perception time consist of child friendly methods, which
require the participants to indicate what they perceive on the screen, using
verbal responses, matching techniques, button presses or eye movements. Most
children experience such measurements as a series of games. Eye movements will
be recorded with a remote, video-based eye tracker. Participants will be asked
to come to Zeist, Nijmegen or if possible will be tested at their own school.
No physical or physiological discomfort is expected, therefore the risks are
considered to be negligible.
Children with complaints of slow vision regularly visit Bartiméus or
Koninklijke Visio. Especially for children these complaints have important
consequences in daily life, particularly at school. Therefore, it is important
to establish whether visually impaired children and children with CVI also have
problems of slower visual perception. Because we expect developmental
components in both perception time as well as oculomotor behaviour, it is
important to gather normative data from different age groups.
Geert Grooteplein 21
Nijmegen 6525EZ
NL
Geert Grooteplein 21
Nijmegen 6525EZ
NL
Listed location countries
Age
Inclusion criteria
Normally sighted participants (controls): a visual acuity >= 0.8, aged 4 to 60
years old., Visually impaired children: a visual acuity >= 0.05 and <= 0.4 and
born after normal pregnancy and with a normal birth weight and without
additional impairments, aged 4 to 17 years old., Children with cerebral visual
impairment (CVI): diagnosed with CVI and having visited Bartiméus for
rehabilitation, treatment, diagnosis or checkups, aged 4 to 17 years old.,
Normally sighted children with an apparent delay in perception: a visual acuity
>= 0.8, normal visual field, fine motor skills sufficient to perform the tests.
Observations of ophthalmologists or optometrists of slow visual perceptual
speed and/or complaints about slow vision, aged 4 to 17 years old.
Exclusion criteria
For the normally sighted participants (controls):
Fine motor skills insufficient to perform the tests., For the visually impaired
children:
Retinal pathology leading to a central scotoma,
Diagnosis of additional mental impairments., For the children with CVI:
Severe mental retardation and/or motor problems leading to problems to
understand or execute all the tests used in the study., Normally sighted
children with an apparent delay in perception: Fine motor skills insufficient
to perform the tests.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL48708.091.14 |
| OMON | NL-OMON21874 |