The objective of this study is to determine the difference in maximal dorsoflexion angle of the ankle when performing the weight bearing dorsoflexion lunge test between patients with a chronic midportion Achilles tendinopathy and healthy controls.
ID
Source
Brief title
Condition
- Tendon, ligament and cartilage disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome is the difference in the maximal dorsoflexion angle of the
ankle when performing the weight bearing dorsoflexion lunge test between
patients with a chronic midportion Achilles tendinopathy and healthy controls.
Secondary outcome
Secondary outcomes are the difference in strength of the gastrocnemius and
soleus muscle, flexibility of the gastrocnemius and soleus muscle when
performing an one leg jump and and quantification of the neovascularisations
using ultrasound between patients with a chronic midportion Achilles
tendinopathy and healthy controls.
Background summary
Overuse injury of the midportion of the Achilles tendon is a common entity in
athletes and sedentary persons. As an example, Elite running athletes have a
lifetime risk of sustaining and Achilles tendon injury of 52%. The diagnosis is
made when the classic triad is present: local tenderness, local swelling and a
decreased weight bearing capacity.
The pathogenesis of an Achilles tendinopathy is degeneration of collagen fibers
and neovascularization. Chronic tendon overload is considered to be the main
reason for developing an Achilles tendinopathy. Several other risk factors for
developing Achilles tendinopathy have been proposed, such as a reduced
dorsiflexion of the ankle, obesity, excessive pronation of the foot, decreased
mobility of the subtalar joint and a decreased flexibility and force of the
gastrocnemius-soleus complex. The reduced dorsiflexion of the ankle could
potentially be used to advise the performance of stretching exercises of the
calf. At this moment however, scientific evidence for the difference between
patients and healthy controls is scarce.
Study objective
The objective of this study is to determine the difference in maximal
dorsoflexion angle of the ankle when performing the weight bearing dorsoflexion
lunge test between patients with a chronic midportion Achilles tendinopathy and
healthy controls.
Study design
This study has a cross-sectional study design. Healthy control will be compared
with patients who are included in the double- blind, placebo-controlled
intervention study which is in progress (HAT study).
Study burden and risks
The burden due to participation will be 45 minutes in a single visit. During
this visit, clinical tests as described above will be performed end a
questionnaire will be carried out. Therefore, the burden due to participation
is expected to be minor.
Burgemeester Banninglaan 1
Leidschendam 2262 BA
NL
Burgemeester Banninglaan 1
Leidschendam 2262 BA
NL
Listed location countries
Age
Inclusion criteria
- Age 18-70 years.
- Absence of clinical diagnosis of chronic midportion Achilles tendinopathy: Painfull swelling of the Achilles tendon, 2-7 cm proximal to it*s calcaneal insertion.
Exclusion criteria
- Known to have the following disorders: spondylarthropathy, gout, hyperlipidemia, rheumatoid arthritis and sarcoïdosis.
- Inability to perform a heavy load eccentric exercise program
- Recently prescribed drugs (within 2 months) with a putative effect on symptoms and tendon healing (quinolone antibiotics, corticosteroids)
- Presence of pregnancy
- Previous Achilles tendon rupture
- A medical condition that would affect safety of an injection (e.g. peripheral vascular disease, use of anticoagulant medication)
- Inability to give informed consent
- Participation in other concomitant treatment programs
- Participant has already one side included in this study
Design
Recruitment
metc-ldd@lumc.nl
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
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Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL61465.098.17 |