The aim is to target cognitive functioning (i.e., attention, working memory, and executive functioning,) and consequentially psychosocial functioning (i.e., participation, family functioning and quality of life) of children and adolescents (age 8-18…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
niet-aangeboren hersenletsel
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Three cognitive tests have been selected as primary outcome measures to assess
change in attention (score on d2), working memory (score on Corsi Block-Tapping
Test), and executive functioning (score on Concept Shifting Task). The main
study parameters are the change in performance from baseline measurement (T0)
to post intervention measurement (T1, i.e., 6 to 8 weeks after T0) on each of
these three tests.
Secondary outcome
For a broad overview of cognitive functioning after the intervention period,
additional cognitive tests have been selected as secondary outcomes.
Furthermore, subjective cognitive functioning (as measured with questionnaires)
and psychosocial functioning (i.e., participation, family functioning and
quality of life) of children and adolescent with ABI are considered secondary
study parameters.
Background summary
Children and adolescents with acquired brain injury (ABI) frequently report
problems with cognitive functioning and consequently problems with psychosocial
functioning. While these problems are usually targeted with cognitive
rehabilitation, evidence from well-designed studies into effectiveness of
cognitive rehabilitation is lacking in this population. Computer-based
cognitive retraining (CBCR) is a promising cognitive rehabilitation method, but
has been insufficiently investigated in children and adolescents with ABI.
Study objective
The aim is to target cognitive functioning (i.e., attention, working memory,
and executive functioning,) and consequentially psychosocial functioning (i.e.,
participation, family functioning and quality of life) of children and
adolescents (age 8-18) with ABI by use of a CBCR combined with explicit
strategy instruction.
Study design
The study has a multicentre pretest-posttest trial design. There will be three
time points of measurement: baseline (T0) before the start of the intervention
period, post intervention (T1), and follow-up three months after the
intervention (T2).
Intervention
All participating children and adolescents will be offered a 6-week CBCR
program targeting a wide range of cognitive functions (i.e., attention, working
memory, and executive functioning) combined with explicit strategy instruction.
Participants train 5 times a week for approximately 30 minutes and attend 45
minutes of explicit strategy instruction per week.
Study burden and risks
There are no known risks associated with participation in this study. The
experimental intervention offered to participants in the intervention group has
potential to improve cognitive and psychosocial functioning. Neuropsychological
assessment and filling in questionnaires is in general not experienced as
stressful or invasive.
Universiteitssingel 40
Maastricht 6229ER
NL
Universiteitssingel 40
Maastricht 6229ER
NL
Listed location countries
Age
Inclusion criteria
- Age between 8 and 18 years
- Diagnosed with ABI (e.g., traumatic brain injury, brain tumour, stroke,
encephalitis, meningitis, and hypoxia).
- At least 6 months post injury
- Experiencing problems with at least one of the to be trained cognitive
functions (i.e., attention, working memory, or executive functioning)
Exclusion criteria
- General level of intelligence lower than 80 (important with regard to the
reliability and validity of the test administration)
- Unable to perceive visual stimuli and/or control the arrow keys of a
keyboard/ a computer mouse
- Previously trained with a CBCR
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL54523.068.15 |
| OMON | NL-OMON19870 |