To correlate structural modifications with visual function in patients after macula-on retinal detachment.
ID
Source
Brief title
Condition
- Retina, choroid and vitreous haemorrhages and vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Macular function (as measured by microperimetry) and structural modifications
(as measured by OCT and OCTA).
Secondary outcome
Visual acuity
Contrast sensitivity
Color sensitivity
Metamorphopsia
Aniseikonia
Background summary
Vitreoretinal surgery for rhegmatogenous retinal detachment has a high
reattachment rate and it is assumed that macular damage is limited as the
macula is not involved. However, despite anatomically successful surgery for
macula-on retinal detachment, patients can perceive unexplainable loss of
vision1*4. Studies have shown structural modifications of the macula after
macula-on retinal detachment, but these findings have not yet been correlated
with visual function in long term5,6. We hypothesize that damage induced by the
retinal detachment extends beyond the detached area, towards the fovea, which
may result in structural modifications and visual function loss.
Study objective
To correlate structural modifications with visual function in patients after
macula-on retinal detachment.
Study design
Prospective observational.
Study burden and risks
Inconvenience of the additional tests is minimal. Risks associated with
participation are negligible. Extra time for research assessments is estimated
to be 8 hours.
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Listed location countries
Age
Inclusion criteria
At least 18 years of age
Primary rhegmatogenous retinal detachment without macular involvement: > 1250
µm from fovea
Healthy contralateral eye
Exclusion criteria
Redetachment
Tractie
Proliferative retinal vascular disease
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL72120.078.19 |