To evaluate the diagnostic potential of the elispot Legionella for identifying patients with Legionella disease
ID
Source
Brief title
Condition
- Bacterial infectious disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Diagnostic potential of the elispot to identify Legionella disease patients
Secondary outcome
To evaluate the T-cell respons in time in patients with a Legionella infection
Background summary
Legionellosis is difficult to diagnose
Study objective
To evaluate the diagnostic potential of the elispot Legionella for identifying
patients with Legionella disease
Study design
Observational study to evluate a new diagnostic tool
Study burden and risks
None besides the risk of a venapunction
Bosboomstraat 1
Utrecht 3582KE
NL
Bosboomstraat 1
Utrecht 3582KE
NL
Listed location countries
Age
Inclusion criteria
(group1) Hospitalized Patients with a proven Legionella infection (positive Legionella urine antigen test/ culture/ PCR) of which a subgroup willing to participate to the follow up study
(group 2) healthy volunteers matched for age and gender
(group 3) Patients with clinical presentations of pneumonia and a proven other pathogen
Exclusion criteria
• immunosuppressive medication
• < 18 years
• Incapacitated patients not able to give informed consent
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL68503.100.18 |