Do people with cluster headache exhibit an increased tendency towards risk- and reward-seeking behaviour as quantified by an array of psychometric tests and the Balloon Analogue Risk Task (BART), compared to age- and sex-matched healthy controls and…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Hoofdpijn
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
- Psychometric test (subjective): Total score on the Zuckerman Sensation
Seeking Scale
- Balloon Analogue Risk Task (BART, objective): Total number of pumps during
second trial
Secondary outcome
- Total scores on the array of psychometric tests
o The Zuckerman*s Sensation Seeking Scale version-V (SSS-V) * a general measure
of sensation-seeking
o The Barret Impulsiveness Scale (BIS) * a 30 item questionnaire designed to
assess the personality/behavioural construct or impulsiveness.
o Gormally*s Binge Eating Scale (BES) * a 16 item questionnaire which has been
used in studies on eating behaviours to diagnose binge eating disorder.
o The World Health Organization-developed AUDIT (Alcohol Use Disorders
Identification Test) screen * a 10-question screening tool, developed by the
WHO, which has been designed as a as a simple and brief method of screening for
excessive drinking.
o The CAGE questionnaire for substance abuse-adapted to include drugs * a
4-question tool widely used in primary care clinics as an initial screen for
alcohol and substance abuse.
o Gamblers Anonymous*s 20 Questions (GA20) * a screening tool for detection of
problematic gamblers.
o Hospital Anxiety and Depression Scale (HADS) * a 14 item questionnaire
designed to assess anxiety and depression in the general population.
o Additional screening questionnaire (ASQ) * Based on a questionnaire developed
in a previous study to asses life-time drug use with the addition of questions
about tattoos and previous head trauma.
- Total scores on the BART
Background summary
Cluster headache is a severe primary headache disorder. In clinical anecdotes,
people with cluster headache frequently report use of tobacco and illicit
drugs. Furthermore, addictive behaviours and tattoos are considered to be more
common in people with cluster headache than in the general population. The
causality of these associations remains unclear. A common biological
susceptibility has been proposed, predisposing people to both addictive
behaviour and cluster headache. On the other hand, a role of illicit drug
exposure in cluster headache pathophysiology has been suggested. The increased
use of tobacco and illicit drugs could also reflect attempts to treat cluster
headache attacks. In this explorative study we will assess both subjective and
objective measures reflecting addictive behaviour and risk- and reward seeking
in cluster headache. This will add to the clinical knowledge of cluster
headache and possible lead to insights in a common biological susceptibility.
Study objective
Do people with cluster headache exhibit an increased tendency towards risk- and
reward-seeking behaviour as quantified by an array of psychometric tests and
the Balloon Analogue Risk Task (BART), compared to age- and sex-matched healthy
controls and compared to age- and sex-matched people with migraine?
Study design
Case-control study
Study burden and risks
There is no risk associated with participation in this study. To minimize the
burden, the questionnaires and BART will be performed, if possible, on the same
day as the outpatient hospital visit.
Since questionnaires will be administered regarding addictive behaviour and
personality and these questionnaires will be scored, participants are asked
beforehand if they would like to be informed about the results. It will be
stressed however that a diagnosis cannot be made by a questionnaire and the
results will only be indicative.
Albinusdreef 2
Leiden 2333ZA
NL
Albinusdreef 2
Leiden 2333ZA
NL
Listed location countries
Age
Inclusion criteria
Inclusion Criteria * Cluster Headache (eCH & cCH) group:
* Age 18-64 years
* Normal or corrected vision with acuity up to 20/60
* Presence of episodic (n<=35) or chronic (n<=35) cluster headache, diagnosed according to the International Classification of Headache Disorders criteria, 3rd edition (ICHD-3, 3.1.1) ;Inclusion Criteria * Migraine group:
* Age 18-64 years
* Normal or corrected vision with acuity up to 20/60
* Presence of migraine with or without aura, diagnosed according to the International Classification of Headache Disorders criteria, 3rd edition (ICHD-3, 3.1.1)
* Matched to CH patients in age, sex. ;Inclusion Criteria * Healthy Controls:
* Age 18-64 years
* Normal or corrected vision with acuity up to 20/60
* Matched to CH patients in age, sex.
Exclusion criteria
* Diagnosis of uncorrected visual problems (myopia/presbiopia, peripheral vision problems or legal blindness)
* Current diagnosis of generalized anxiety disorder, depression or other psychiatric illness
* Other acute, unstable medical conditions or serious chronic diagnoses
Design
Recruitment
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL68327.058.18 |