The primary objective is to identify joint trajectories of mobility and perceived fatigue from hospital admission to 6 months post-discharge in acutely admitted hospitalized older patients. Secondary objectives are:(1) to explore associations of…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
kwetsbaarheid, veroudering
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
main study parameters are repeated measurements of mobility (assessed by De
Morton Mobility Index), and perceived fatigue (assessed with the Pittsburgh
Fatigability Scale).
Secondary outcome
Secondary objectives are the capacity of the physiologic system to enhance
homeostasis during illness is reflected by the capacity of different organ
systems to restore deviating values back to normal values. Physiologic systems
are expressed by cognitive, immunological, endocrine, musculoskeletal,
cardiovascular, respiratory, and renal responses.
Furthermore, age, sex, educationlevel, depression, comorbidity, medication,
pain, in-hospital activity, and the capacity of the physiologic system to
enhance homeostasis will be used in the analyses for the first secondary
objective.
Finally, in the qualitative interview, feasibility of an intervention to
prevent hospital associated decline will be investigated. The use of a wearable
(Fitbit) in combination with a digital application will be evaluated using two
questions addressing user acceptability.
Background summary
Hospital admission is a major life event, often leading to deterioration in
physical functioning. Physical functioning is of great importance for
independent living in older persons. Therefore interventions to prevent
functional decline in older adults are important. Since fatigue is the most
prevalent symptom during hospitalization, and it is suggested to be a
pre-clinical marker for reduced resilience of physiological systems, it may be
an interesting marker for hospitalized older patients regarding recovery and
adverse health outcomes like functional decline.
Study objective
The primary objective is to identify joint trajectories of mobility and
perceived fatigue from hospital admission to 6 months post-discharge in acutely
admitted hospitalized older patients.
Secondary objectives are:
(1) to explore associations of potential predictors and clinical markers of the
physiological system measured during hospital admission related to each
trajectory.
(2) to explore the feasibility of interventions to prevent functional decline
during hospital admission
(3) to explore the feasibility of the use of wearables and a digital
application for monitoring physical activity after hospital discharge among
geriatric patients aged 70 years and older.
Study design
An observational cohort study
Study burden and risks
Participation consists of filling in questionnaires (total duration maximal 35
min.) and performing physical tests (total duration about 35 min.) at four
different moments, including two during hospitalization; to wear a tight worn
device, the MOX, during their hospital stay; to wear a wrist worn device
(Fitbit) during hospital stay up to 3 months pst discharge; and, optional,
participating in a qualitative interview regarding opinions and potential
barriers and facilitators towards physical activity during hospital admission
(total duration maximal 30 min.).
In total, there are four moments of assessments: first within the first 3 days
of their hospital stay (questionnaires, physical test, putting on the MOX and
Fitbit); second within 24 hours before discharge (questionnaires, physical
tests, collecting the MOX), and the third and fourth moments of assessment are
home visits at 3 and 6 months post discharge (questionnaires and physical
tests). For the qualitative interview a separate appointment will be made.
Hanzeplein 1
Groningen 9713GZ
NL
Hanzeplein 1
Groningen 9713GZ
NL
Listed location countries
Age
Inclusion criteria
aged 70 years or older;
willing to participate
medically able to participate
providing informed consent.
Exclusion criteria
1. no understanding of the Dutch language;
2. lack of decision making capacity, due to:
a.previously diagnosed dementia;
b. delirium or other conditions that influence decision making capacity;
3. hospital admission for more than 48 hours, due to:
a.transfer from another hospital to the UMCG;
b.transfer from another ward (e.g. Intensive Care Unit (ICU), or rehabilitation
center) to an internal medicine ward in the UMCG;
4. expected stay in hospital for less than 48 hours or when the patient is
expected to die within <48 hours;
5. any medical condition that prevents the patient to safely participate in
assessments that require light physical activities.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL64465.042.17 |