Primary objective: to determine the association between social and cognitive performance of preterm-born young adults and their early motor repertoire up to 3 months after term. Secondary objective: to describe the social and cognitive functioning…
ID
Source
Brief title
Condition
- Neonatal and perinatal conditions
- Age related factors
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary endpoint: Total IQ (measured by the Wechsler Adult Intelligence Scale,
WAIS), with subdivision into verbal and performance IQ.
Secondary outcome
Secondary endpoints: neuropsychological development measured by a series of
tests and questionnaires, anthropometry by assessment, and reported
health-related behaviors, perceived health, social relations, social cognition,
time spending, school or work performance and pain perception.
Background summary
When an infant is born, it is difficult to predict the outcomes on the various
domains of development, particularly if risk factors for an abnormal
development are present, such as preterm birth. It is known that preterm-born
children experience more social and cognitive problems in comparison with the
norm population. Much less is known, however, about their functioning at
adulthood.
Study objective
Primary objective: to determine the association between social and cognitive
performance of preterm-born young adults and their early motor repertoire up to
3 months after term. Secondary objective: to describe the social and cognitive
functioning of preterm-born young adults compared with healthy controls.
Study design
Prospective longitudinal cohort study
Study burden and risks
At home, questionnaires will be filled in by the young adults regarding
socio-demographic data (including general questions regarding socioeconomic
status (SES), family composition, major life-events in the family, medical
history, school and work performance, perceived health and pain perception),
perceived behavioral and emotional problems, mental health, executive
functioning, and signs of Attention Deficit Hyperactivity Disorder. This will
take approximately 60 to maximally 90 minutes.
We will then invite the young adults to the UMCG. During that visit with a
total time-span of 3 to maximal 3.5 hours including instructions and 2 short
breaks of 15 minutes we will perform:
- Neuropsychological tests performed for intelligence (IQ), information
processing speed and attention, executive functioning, (visual-spatial/verbal)
memory and social cognition.
- A limited physical examination, including measurements of weight, length,
head, waist and upper arm circumferences, blood pressure, and percentage body
fat. For estimating body fat percentage, Bioelectrical Impedance Analysis (BIA)
will be used.
Hanzeplein 1
Groningen 9713GZ
NL
Hanzeplein 1
Groningen 9713GZ
NL
Listed location countries
Age
Inclusion criteria
Patient group:
Gestational age < 34 weeks
Written informed consent of participating young adults
Control group:
Written informed consent of participating young adults
Exclusion criteria
Patient group:
None
Control group:
Prematurity
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL66718.042.18 |