To optimise, test and evaluate new and modified MRI sequences and technology under a test-retest scheme. To validate new sequences in patients in order to reduce MRI protocols in the future.
ID
Source
Brief title
Condition
- Joint disorders
- Metastases
- Central nervous system infections and inflammations
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Healthy volunteers:
Parameters of image quality: artefacts, signal to noise, contrast to noise,
reproducibility, accuracy.
Patients:
Quantitative MR (T1, T2, PD).
Secondary outcome
NA
Background summary
New or modified MRI sequences/technologies has to be evaluated in healthy
volunteers and patients in order to assess the additional value of these
sequences/technologies in the visualisation and quantification of tissues and
organs.
Study objective
To optimise, test and evaluate new and modified MRI sequences and technology
under a test-retest scheme. To validate new sequences in patients in order to
reduce MRI protocols in the future.
Study design
Observational diagnostic study.
Study burden and risks
Burden: MRI examination for maximum 60 minutes in healthy volunteers and 10
minutes in patients. Exposure to acoustic noise. Risks: incidental findings.
's Gravendijkwal 210
Rotterdam 3015 CE
NL
's Gravendijkwal 210
Rotterdam 3015 CE
NL
Listed location countries
Age
Inclusion criteria
Healthy subjects:
- Healthy subject (defined as a volunteer who is not referred to Erasmus MC
with signs and symptoms of disease)
- At least 18 years old and not older than 50 years old.
- Signed informed consent
Patients:
- Patients with brain tumor with previous conventional scan and referred to
conventional treatment.
- Adults
- Signed informed consent
Exclusion criteria
Healthy subjects:
- Subjects with a typical contra-indication to an MRI exam.
- Subjects with metal implants.
- Woman who are pregnant or lactating
- Having any physical or mental status that interferes with the informed
consent procedure
Patients:
- Subjects with a typical contra-indication to an MRI exam.
- Subjects with metal implants.
- Woman who are pregnant or lactating
- Having any physical or mental status that interferes with the informed
consent procedure
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL64907.078.18 |