The main objective of this study is to perform a quality assessment on several new techniques, used in the laboratory of Translational Cancer Genomics and Proteomics
ID
Source
Brief title
Condition
- Miscellaneous and site unspecified neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary endpoint of this study is to assess quality parameters (intra- and
interlaboratory variation, time-to-processing influence, transport influence)
of emerging liquid biopsy techniques.
Secondary outcome
Not applicable
Background summary
Different liquid biopsy assays are already established in oncology research and
clinical settings, like circulating tumor DNA assays and quantification of
circulating tumor cells using the FDA-approved CellSearch® system. As we move
towards the future, liquid biopsies can help us gain insight in tumor evolution
and clonal expansion and ultimately be used to choose the best personalized
treatment for the individual patients. To reach that aim, emerging techniques
have to be of solid quality. The influence of technical aspects on emerging
techniques are not yet fully clear, like inter- and intralaboratory differences
and the influence of time-to-analysis.
Study objective
The main objective of this study is to perform a quality assessment on several
new techniques, used in the laboratory of Translational Cancer Genomics and
Proteomics
Study design
Observational study
Study burden and risks
Risk and burden of participating in this study are negligible. Subjects will
undergo no extra interventions, since the blood draw is during a regular visit.
The treating physician will assess if the subject is fit enough to donate this
amount of blood.
Dr Molewaterplein 40
Rotterdam 3015 GD
NL
Dr Molewaterplein 40
Rotterdam 3015 GD
NL
Listed location countries
Age
Inclusion criteria
1. Metastatic cancer
2. Fit enough to deliver a maximum of 120 mL of peripheral blood, assessed
by treating physician
3. Written informed consent
Exclusion criteria
None specified
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL75196.078.20 |