Primary Objective: To access the geometries and the motions of thumb base joint.Secondary Objective(s): To assess factors (such as gender, hand dominance, and hand size) that might affect the bone geometries and the joint motions.
ID
Source
Brief title
Condition
- Joint disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Statistical models of shapes and motions will be developed based on the
collected data.
Secondary outcome
The effect of factors, such as gender, hand dominance, and hand size, on the
geometries and the motions will be assessed.
Background summary
Arthritis is a disease that leads to irreversible joint damage and disability,
which greatly affects the living quality. Joint replacement is one of the
treatments. More research is needed to optimize the implant design for the
joints at wrists. We will investigate the shape and motion of thumb base joint
by developing statistical models.
Study objective
Primary Objective:
To access the geometries and the motions of thumb base joint.
Secondary Objective(s):
To assess factors (such as gender, hand dominance, and hand size) that might
affect the bone geometries and the joint motions.
Study design
Quantitative study: Statistical analysis and modeling of the bone geometries
and the thumb base joint motion of the 4D CT data.
Study burden and risks
Participants will receive radiation doses during their participation. However,
the dose is negligible and the effect will be controlled. There is no direct
benefit to the participants. But, the study could help to develop a more
comprehensive understanding of the thumb base joint. The results can provide
guidance and improvement of thumb base implant designs. The results may also be
useful for the diagnosis and treatments of wrist arthritis.
Reniner de Graafweg 5
Delft 2625AD
NL
Reniner de Graafweg 5
Delft 2625AD
NL
Listed location countries
Age
Inclusion criteria
1) No history of trauma or disease in both wrists;
2) More than 18-year old
3) Voluntarily participate in and sign the informed consent
Exclusion criteria
1) Volunteers who refuse to sign the informed consent;
2) Volunteers who have a history of hand trauma or disease with either wrist;
3) Volunteers who are suggested not to take extra radiation dose for other
purposes, such as pregnancy and breastfeeding.
Design
Recruitment
metc-ldd@lumc.nl
metc-ldd@lumc.nl
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL70432.058.19 |