The general objective of this study is to gain more understanding of motor and cognitive impairment and the way these two are linked after stroke. There are two more specific objectives: exploring (1) the link between motor and cognitive impairment…
ID
Source
Brief title
Condition
- Structural brain disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary parameters are motor and cognitive impairment after stroke
Secondary outcome
The link between motor and cognitive impairment
Background summary
The prevalence of both motor and cognitive impairment after stroke is high and
persistent. Focus of attention in both patients, proxies and professionals in
the first weeks to months after stroke is usually on visible motor impairment,
like paresis. The often invisible cognitive impairment might stay underexposed
for a considerable amount of time. Nevertheless, cognitive impairment affects
both rehabilitation success and quality of life of both patient and their
carers. More information is needed about possible links between specific motor
and cognitive impairment after stroke as well as about the possibility to use
motor impairment to predict cognitive impairment.
Study objective
The general objective of this study is to gain more understanding of motor and
cognitive impairment and the way these two are linked after stroke. There are
two more specific objectives: exploring (1) the link between motor and
cognitive impairment after stroke and (2) the possibility to use motor
impairment to predict cognitive impairment in the first two years after stroke.
Study design
By means of a prospective follow-up study, stroke patients will be assessed
with both motor and cognitive instruments on three separate occasions: at
three, twelve and twenty-four months after stroke. Both objective tasks and
more subjective ratings scales and questionnaires will be used.
Study burden and risks
During this study there will be three assessments, each taking approximately
two hours and consisting of an interview and a neuropsychologisch assessment in
the hospital setting. The total burden for participants is estimated to be six
hours in a period of two years, divided in three assessments each lasting for
two hours. The study is non-invasive, there are no specific risks and
participants will be compensated for traveling expenses. With the results of
this study we aim to gain more understanding of motor and cognitive impairment
after stroke and the way these two are linked. The overall aim of the study is
to improve the future care for stroke patients and therefore health benefits
for participants are not expected. In case of individual results that give rise
to concern, participants will be referred to their physician. Due to the
clinical and social importance of the aims of this study and the fact that
participating does not result in specific risks, the burden for the
participants seems justifiable.
de Run 4600 de Run 4600
Veldhoven 5504 DB
NL
de Run 4600 de Run 4600
Veldhoven 5504 DB
NL
Listed location countries
Age
Inclusion criteria
Clinical diagnosis of stroke (first or recurrent), ischaemic or intracerebral
haemorrhagic.
Age > 18.
Sufficient understanding of Dutch language.
Exclusion criteria
Clinical diagnosis of Transcient Ischemic Attack (TIA) or Subarachnoidal
bleeding (SAB).
Premorbid cognitive decline as defined by a IQcode score > 3.6.
Premorbid severe psychiatric or neurological problems, for example a delirium
Communication problems which make neuropsychological examination and/or the use
of questionnaires impossible (e.g. blindness, deafness, severe aphasia).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL56866.015.16 |