The development and optimization of new and existing MRI protocols and processing techniques required for advanced anatomical and functional imaging in the research and clinical setting.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
geen specifieke aandoening te benoemen. de ontwikkelde protocollen en beeldverwerkingstechnieken kunnen voor verschillende aandoeningen worden gebruikt.
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The development and optimization of new and existing MRI protocols and
processing techniques required for anatomical and functional imaging in the
research and clinical setting. In addition new methods will be developed for
image processing.
Secondary outcome
Not applicable.
Background summary
Currently several MRI systems from different magnetic field strengths are
available at the UMCU. The systems offer a wide range of opportunities for
non-invasive studies of anatomy, structure, function and metabolism in
patients. For a number of diseases new, improved imaging techniques are
required. To be able to apply these (new) clinical improvements, further
technical improvements are required. Before the improved techniques can be
used, various technical issues will have to be solved before the technology can
be used for clinical research and patient care. During this proces, there is a
need for (healthy) subjects to optimize the techniques before the technology
can be used in patients. In this study healthy volunteers will be included in
studies that aim to optimize the technique and the use of MRI in all field
strengths and to develop new processing techniques.
Study objective
The development and optimization of new and existing MRI protocols and
processing techniques required for advanced anatomical and functional imaging
in the research and clinical setting.
Study design
This is an observational study in which the possible applicability of newly
developed MRI scanning and processing techniques is assessed.
Study burden and risks
No benefits are expected for the volunteers. The study can lead to insights
about the possible added value of using MRI techniques for patients and of new
methods of image processing in the future.
No risks or adverse effects are known for patients undergoing MRI when they are
screened according to the MRI safety criteria.
Participants will be scanned during 60 to 90 minutes.
Heidelberglaan 100
Utrecht 3584 CX
NL
Heidelberglaan 100
Utrecht 3584 CX
NL
Listed location countries
Age
Inclusion criteria
- >= 18 years
- Capable and prepared to sign an informed consent
Exclusion criteria
- Contraindication for MRI scanning as listed in the MRI screening form,
according to the current MR safety guidelines
- Neurological or psychiatric diagnosis
- (possible) pregnancy
-Refusal of subjects to be informed of chance findings possibly relevant to
their health
In the event that the RespirAct system is used for a sub-study:
- Unwilling or unable to cooperate with breathing protocol or keeping still;
- Medical contraindications to limited hypercapnia (known metabolic acidosis or
alkalosis);
- Standard contraindications for using the RespirAct RA-MRTM MRI UNIT (see D2
IMDD 2.5 contraindications);
- Known cerebrovascular, cardiovascular or pulmonary (or other) disease
- concurrent severe or uncontrolled medical disease (e.g., active systemic
infection);
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL53099.041.15 |