Assess the proportion of clients and staff members of homelessness services with positive SARS-CoV-2 PCR-infection and antibodies results, and its determinants.
ID
Source
Brief title
Condition
- Viral infectious disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter is the proportion of individuals with a positive
SARS-CoV-2 PCR- and antibody result among all individuals who are tested
(antibody and PCR separate).
Secondary outcome
1. socio-demographic, clinical and lifestyle factors associated with the
presence of SARS-CoV-2 infection and antibodies
2. proportion of staff members and clients who have the intention to get
vaccinated against COVID-19
Background summary
Individuals experiencing homeless may be more susceptible to SARS-CoV-2
infection and severe COVID-19 disease due to their lifestyle including (lack
of) living accommodation and increased risk of chronic and physical conditions.
These factors might also affect testing uptake in this group. Whilst additional
emergency accommodation has been available to people experiencing homelessness
in the Netherlands since the start of the pandemic, little is known about the
impact of these interventions in preventing SARS-CoV-2 spread in this group.
Meanwhile, SARS-CoV-2 outbreaks as well as a high seroprevalence of antibodies
have been reported in people experiencing homelessness in other countries
outside of the Netherlands. Moreover, given fears doe an increase in SARS-CoV-2
infections due to the fast-spreading UK strain, high vigilance is needed to
prevent outbreaks in settings and communities at potentially high risk of
infection acquisition and transmission.
Study objective
Assess the proportion of clients and staff members of homelessness services
with positive SARS-CoV-2 PCR-infection and antibodies results, and its
determinants.
Study design
Cross-sectional study
Study burden and risks
Participants will undergo a single nasopharyngeal swab for PCR-testing and a
finger-stick to collect one to two drops of whole blood from the participant
for antibody testing. Both a nasopharyngeal swab and a fingerstick may create
discomfort, slight bruising (blood collection) and mild pain. Afterwards,
individuals will complete a short questionnaire about their health, testing
history and willingness to vaccinate which will require about 15 minutes of
their time. Clients with positive PCR results will not be able to enter or stay
at the homeless service where they are being tested, and will be offered
transportation and stay at another emergency shelter specially designed to
accommodate COVID-19 (suspected) cases according the current protocol of GGD
Amsterdam . Staff members of homeless shelters with a positive PCR test will be
asked to isolate at home according to the RIVM current protocol. Regarding
group relatedness, the sampling is considered to be necessary since it is the
only approach to gain insight in the prevalence of SARS-CoV2 infection and
antibodies and its determinants among staff members and individuals
experiencing homelessness.
Nieuwe Achtergracht 100
Amsterdam 1018 WT
NL
Nieuwe Achtergracht 100
Amsterdam 1018 WT
NL
Listed location countries
Age
Inclusion criteria
- Able to understand the research information and provide informed consent
- >=18 years old
- Staff or client of homeless service
- Sufficient understanding of Dutch, English or Polish
Exclusion criteria
- Younger than 18 years old
- Mental disorder or cognitive problems that in the view of the personnel would
interfere with the study procedures, or the decision to participate in the
study.
- Not being able to understand Dutch, English or Polish
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL76623.018.21 |