The present study aims to assess the effectiveness of a religion-adapted CBM intervention compared to a standard, non-religion CBM intervention, and sham intervention based on approach bias modification (ApBM).
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Stoornis in alcoholgebruik
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome will be recovery consisting of (1) the percentage of days
abstinent the past month at four months follow-up using the Timeline Followback
(TFLB) method and (2) meaning in life using the Multidimensional Existential
Meaning Scale (MEMS).
Secondary outcome
Secundary outcomes will be training satisfaction with a 9-point Likert scale
and AUD symptoms with the Leeds Dependence Questionnaire (LDQ).
Background summary
Alcohol-related cues in the environment are important triggers for relapse in
patients with Alcohol Use Disorder (AUD). These cues may automatically activate
motivational approach tendencies that promote alcohol seeking. Through
computerized cognitive bias modification (CBM), the tendencies of patients with
AUD to approach alcohol can be reduced. CBM methods are helpful but can be
improved by the involvement of patients' characteristics of religiosity and
meaning in life (MiL).
Study objective
The present study aims to assess the effectiveness of a religion-adapted CBM
intervention compared to a standard, non-religion CBM intervention, and sham
intervention based on approach bias modification (ApBM).
Study design
Using a double-blind multi-arm parallel randomized controlled trial (RCT)
procedure (ratio 1:1:1), 120 patients with AUD will be randomized into one of
three conditions (religion-adapted ApBM, standard ApBM, or sham ApBM), with
personalized stimuli and will be evaluated on training satisfaction after the
training, abstinence, AUD symptoms and MiL four months after the intervention.
Intervention
In addition to treatment as usual (TAU) all participants receive four sessions
of a 15 minutes training on the computer and responding with a joystick to
self-selected pictures. The training is expected to decrease relapse due
modification of alcohol stimuli and increasing approach of self-selected
religious pictures (religion-adapted ApBM) or non-alcohol pictures (standard
ApBM).
Study burden and risks
Participants will benefit from the ApBM intervention. To our knowledge, there
are no risks associated with the usage of ApBM interventions during
detoxification, but the computer tasks and questionnaire completion may be
stressful.
Provincialeweg 70
Dordrecht 3329 KP
NL
Provincialeweg 70
Dordrecht 3329 KP
NL
Listed location countries
Age
Inclusion criteria
(a) Classified AUD following DSM-5 criteria
(b) Being 18 years of age or older
(c) Being enrolled as a patient for the detoxification program
(d) Speak Dutch fluently
(e) Provide informed consent (IC) before participation
Exclusion criteria
(a) History of severe neurological disorders (like Korsakoff syndrome)
(b) Acute psychotic symptoms
(c) Visual or hand-motoric handicaps
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL75499.018.20 |