There are large interindividual differences in tolerance for night work. The main factors determining this tolerance are largely unknown, and better identifying them - which is the aim of this study - may target preventive and mitigating strategies…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Circadiane ritme
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Compound set of Questionnaires:
- Chronotype Questionnaire
- Visuo-verbal Judgment Task
- Single-item Chronotype Scale: energy level throughout the day
- Munich Chronotype Questionnaire: chronotyping according tot the LIVEMAN-model
(Lethargic, Intermediate/Inconclusive, Vigilant, Evening, Morning, Afternoon,
Napping types)
- Pittsburg Sleep Quality Index (PSQI): sleepquality and sleep quantity
- Brief-Caffeine Expectancy Questionnaire: effects of cafeïne-containing
products
2. Genotyping 5 SNP*s (Adenosine A2A receptor (ADORA2A), Adenosine deaminase
(ADA), Catechol-O-methyltransferase (COMT), Tumor necrosis factor alpha (TNF-α)
en Period2 (PER3)) using the Whatman* FTA* Buccal collection selfkit
Secondary outcome
N/A
Background summary
A substantial part of the Dutch Defense labor force is regularly exposed to
shift work and night work. Night work compromises the individual Circadian
rhythm and may lead to fatigue and sleep problems, or eventually chronic
illness.
Study objective
There are large interindividual differences in tolerance for night work. The
main factors determining this tolerance are largely unknown, and better
identifying them - which is the aim of this study - may target preventive and
mitigating strategies for the least tolerable individuals.
Study design
Participants fill out a compound set of questionnaires regarding sleep behavior
and sleep quality, chronotype and cafeïne intake. Saliva samples are taken from
each participant to analyse their genotype profile on 5 SNPs (see Outcomes).
Associations between questionnaire scores and genotyping are studied. We strive
to include 100 participants into our study.
Study burden and risks
Time investment approx. 45 minutes. No known health risk.
Herculeslaan 1
Utrecht 3584 AB
NL
Herculeslaan 1
Utrecht 3584 AB
NL
Listed location countries
Age
Inclusion criteria
Employee of the Netherlands Armed Forces
Exclusion criteria
Allergic reaction to wearing nitril hand gloves
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL80876.028.22 |