Gait symmetry of patients with an endoprosthetic reconstruction of the knee joint after bone tumour resection.

Measurements are performed in two gait labs. Part of this amendment is the

addition of a second gait lab.

Gait Laboratory 1 is the Technology in Motion (TIM) lab at the LUMC. We use the

interactive walkway. The interactive walkway makes it possible to record

movements without sensors.

Gait laboratory 2 is the movement lab for rehabilitation medicine at the LUMC.

The M-Gait treadmill, a treadmill with multiple calibrated camera setup and

bilateral continuous ground reaction force measurement, was introduced in 2022.

The participant first walks in lab 1 and then in lab 2.



Measurements

- Step time (s) during unperturbed comfortable walking for the affected leg and

the unaffected leg measured with the Interactive Walkway. Step time is the time

interval between initial contact of one leg to the consecutive initial contact

of the contralateral leg;

- Interlimb step time difference (s) to quantify for (a)symmetry;

- Patient reported outcome scores (PROM's) for pain, fear (kinesiophobia) and

health using a numeric rating scale (NRS) administered before gait analysis.



For measurements on the treadmill, the participant will be secured in a

CE-approved harness that is secured to the ceiling with ropes under dynamic

pretension. For measurements with the M-Gait the subjects will walk on the

treadmill for one-and-a-half minute twice: once with the mean walking velocity

measured earlier with the IWW, in order to maximize the comparability with data

obtained with the IWW, and once using self-paced mode, where the treadmill

speed is automatically adapted to the patients walking speed. For both

measurements, the patient will be able to get familiar with walking on the

treadmill for the first 30 seconds and only the last minute of walking will be

recorded and used for analysis.

- Toronto Extremity Salvage Score (TESS), lower extremity version: a validated

questionnaire to assess patient-reported physical outcome;

- Pedometer-assessed (health app, mobile phone) steps per day, if available, of

the last week for assessing the daily physical activity;

- Other walking data recorded in the TIM-lab can be used for possible sub

analyses: centre of body mass, gait speed, step width, step length, stride

time, turning time, stride length, cadence.