This is the first study to combine both objective and subjective daily measures (EMA and actigraphy) to assess fluctuations in suicidal ideation, in real time and in natural settings. The aims of the study are (1) to examine how momentary risk and…
ID
Source
Brief title
Condition
- Suicidal and self-injurious behaviours NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome measure is self-reported suicidal ideation, as measured
with EMA.
The primary predictors include self-reported sleep parameters (sleep
quality/quantity), mood (positive/negative), cognitions (hopelessness,
burdensomeness, loneliness, optimism), stressful events, social interaction
(/isolation), and substance use/coping strategies, as measured with EMA; and
objective sleep parameters (incl. total sleep time, sleep onset latency, sleep
efficiency, wake after sleep onset), as measured with actigraphy.
Secondary outcome
The following self report measures will be assessed at the beginning and at the
end of the cohort study.
1. suicidal ideation
2. depressive symptoms
3. anxiety symptoms
4. quality of life
5. sleep problems
6. cognitive reactivity
7. anger expression
8. borderline personality traits
Acceptability of EMA will also be tested: agreement to participate, compliance
rates, and attrition (operationalized as the number and percentage of
individuals who agree to participate in the study/ valid EMA observations/
individuals who complete the study) and study burden questions (self-report).
Background summary
Suicide is a major cause of death worldwide, and overall, it costs
approximately 800,000 lives annually (WHO, 2017). Although multiple predictors
of suicidal ideation and behavior have been identified (including depression,
hopelessness, stress), they are non-specific and often chronic risk factors
that do not assist the identification of those most at risk in real world
settings. Consequently, suicide is notoriously difficult to
predict. Due to the limitations of the current common approach of assessing
suicidal ideation and its risk factors at infrequent time points and over long
periods of time, little is known about the short-term temporal correlates of
suicidal thought. Less than 1% of suicide research has focused on a time range
of a month or less. Hence, while this is the most crucial period for the
decision-making process of clinicians, we know very little about it. Although
we know that suicidal ideation may fluctuate abruptly, we do not yet know: What
influences these short-term (daily and even hourly) fluctuations? Under which
circumstances are suicidal thoughts more or less prominent?
Research assessing these fluctuations is needed for better understanding and
prediction of suicidal ideation, and real-time methodologies (ecological
momentary assessment, EMA; and actigraphy) are optimally suited for these
purposes.
Study objective
This is the first study to combine both objective and subjective daily measures
(EMA and actigraphy) to assess fluctuations in suicidal ideation, in real time
and in natural settings. The aims of the study are
(1) to examine how momentary risk and protective factors (sleep, mood,
cognitions, stressful events, social interactions, substance use/coping
strategies) lead to increases or decreases in suicidal ideation in the short
term,
(2) to assess the long-term fluctuation of suicidal ideation and identify
proximal predictors for increased/decreased suicidal ideation (weekly for one
year)
(3) to assess the acceptability of electronic symptom self-monitoring (EMA) in
individuals with suicidal ideation.
Study design
A longitudinal cohort study
Study burden and risks
No adverse effects are expected, and participant safety will be monitored
throughout the study.
A potential risk of the study is that participants get sensitized by the
questions (EMA) about suicidal thoughts. If this occurs they can contact the
investigator and can stop the study immediately. Participants are informed
about this risk at the start of the study. Prior studies have shown good
acceptability and no reactivity of assessments (EMA) in suicidal participants
(Husky et al., 2014).
A potential benefit of the study is that, following the assessment period, the
participants will be offered the option of receiving a summary report of their
data that they can also share with their therapist if currently in treatment.
This information can be insightful for the individual and potentially
beneficial for their treatment. Such symptom self-monitoring is increasingly
used in mental health care, and can help mental health professionals obtain
more detailed information about the patient*s functioning, and help them
identify high- and low-risk conditions that are specific for the individual.
Wassenaarseweg 52
Leiden 2333AK
NL
Wassenaarseweg 52
Leiden 2333AK
NL
Listed location countries
Age
Inclusion criteria
1. A history of a suicide attempt or severe ideation in the past 12 months (>=3
Columbia-Suicide Severity Rating Scale, or >=2 if symptoms present in the past 2
months).
2. Aged 18 years or older.
3. Adequate proficiency of both written and spoken Dutch or English.
4. Possession/use of an Android or iOS compatible mobile phone.
5. Willingness to participate in a 1-year longitudinal study.
Exclusion criteria
1. Current diagnosis of Bipolar disorder, a Psychotic disorder, or (severe)
Substance dependence (DSM-5 criteria).
2. Intellectual impairment, dementia or a physical impairment that may prevent
the participant from adequately following the study procedures.
Participants in need of immediate support or treatment will be referred before
enrolment in the study.
Design
Recruitment
metc-ldd@lumc.nl
metc-ldd@lumc.nl
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL71510.058.19 |