The VAT study aims to investigate which factors influence and predict the different areas of recovery. VAT also examines how the content of voices that patients hear should be mapped and registered. We examine whether these factors can predict…
ID
Source
Brief title
Condition
- Schizophrenia and other psychotic disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome measures are changes in clinical recovery (measured with
the PANSS or HADS), functional recovery (housing/employment/studying from the
autobiographical questionnaire) and personal recovery (measured with the Mental
Health Confidence Scale and the Self Esteem Rating Scale).
Secondary outcome
Secundary parameters/outcome measures are the nature of the voices the
participant hear (VOS), the changes and frequency in hearing of the voices (6
items of the PUVI) and how participants view themselves in relation to their
voices (Social Comparison).
Other parameters are several factors related to recovery: general health
(Rand-36), attachment (RAAS), cognitive insight (BCIS), response to
major/traumatic events (TSQ), therapeutic alliance (WAV), self stigma (ISMI),
physical activity (IPAQ, sleep (SCOPA-sleep) and loneliness (de Jong Gierveld).
Background summary
There are an estimated 218.000 people with a severe mental illness, the
majority of which has a psychotic disorder. Additionally one in three Dutch
people experience an anxiety or mood disorder at one moment in their life, of
which a large proportion experience both at the same time. For a long time the
focus of treatment for these patients was to help the recover from the clinical
symptoms. However, recently there has been more attention and recognition for a
broader definition of recovery, where there is room for personal and functional
recovery besides symptomatic recovery. There are many factors that influence
the course of recovery. Several important factors and treatment outcmes of
people with psychotic disorders are yearly monitored in the northern
Netherlands with ROM-Phamous, a routine outcome monitoring program that has
continued to develop this last decade. In its current state, ROM-Phamous does
not accurately measure personal recovery. While there is plenty attention for
clinical symptoms, use of prescribed drugs and physical health, ROM-Phamous
measures few psychosocial factors. Previous research has provided insight into
which psychosocial factors, such as trauma, attachmentstyle and empowerment,
might be of importance. However, these studies were mostly cross-sectional,
whereas we still know little about the course of these factors and how they
interact with each other. It is therefore necessary that we research how all
these different factors relate to one another, how they influence eacht other
over time and how they are related to the different areas of recovery of people
with a psychotic disorder.
Study objective
The VAT study aims to investigate which factors influence and predict the
different areas of recovery. VAT also examines how the content of voices that
patients hear should be mapped and registered. We examine whether these factors
can predict changes in symptomatic, functional and personal recovery. Based on
this we will provide recommendations for measurable constructs that should be
included in annual ROM-Phamous screenings in the future. Its longitudinal
design of the study allows VAT to map the course of several important recovery
factors and to examine how they interact.
Study design
VAT is an observational cohort study.
Study burden and risks
Participants are measured three times with 6 months intervals. During these
measures the examiner conducts a PANSS interview and the participants fill in
self-report questionnaires. Participation to the study has no negative
consequences. There is no intervention with expected effects. We have carefully
considered the amount of variables and the completion-time of the
questionnaires (on average 2 hours), to keep the burden on participants on an
acceptable level. Participants can take a break anytime, interrupt the measure
and continue another day or retract from the study. Questions about the
consequences of a potentially traumatic event or the content of voices could
potentially lead to an emotional respons. The measures will therefore be
conducted by a registered psychologist (GZ-psycholoog) in training to be a
specialized Clinical Psychologist (Klinisch Psycholoog i.o.) or nurse
practitioner in training to be a specialist, who can recognize these signals
and are able to provide immediate care to the participant if necessary. By
participating in the study, patients contribute to the knowledge needed to
improve care for people with a psychotic disorder, including their own care and
future. Considering this is unique information that only people with psychotic
experiences can provide, it is not possible to conduct this study with healthy
volunteers.
Hereweg 80
Groningen 9725AG
NL
Hereweg 80
Groningen 9725AG
NL
Listed location countries
Age
Inclusion criteria
Inclusion criteria psychosis target group
1) There is a psychotic disorder according to the DSM-V; schizophrenia,
schizophreniform, schizo-affective, schizotypal, delusional disorder, psychosis
due to substance/medication use, psychotic disorder not otherwise defined
and/or one of the following DSM-V codes 301. 22, 297.1, 298.8, 295.40, 295.90,
295.70, 293.81, 293.82, 293.89, 298.8, 298.9, 291.9, 292.9.
2) The patient is >= 18 years of age;
3) There is no crisis admission or admission to a closed ward;
4) The patient has sufficient command of the Dutch language.
Inclusion criteria for target group mood disorders
1) There is a bipolar disorder, anxiety or depression disorder according to the
DSM-V;
2) The patient is >= 18 years of age;
3) There is no crisis admission or admission to a closed ward;
4) The patient has sufficient command of the Dutch language language.
Exclusion criteria
Exclusion criteria psychosis target group
1) There is a diagnosis other than schizophrenia spectrum and other related
psychotic disorder according to the DSM-V.
2) The patient is < 18 years of age;
3) There is a crisis admission or admission to a closed ward;
4) The patient has insufficient command of the Dutch language.
Exclusion criteria mood disorder target group
1) There is a diagnosis other than bipolar disorder, anxiety or depression
disorder according to the DSM-V.
2) The patient is < 18 years of age;
3) There is a crisis admission or admission to a closed ward;
4) The patient has insufficient command of the Dutch language.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL64523.042.17 |