Knowledge about which scanning behaviour is optimal, however, is mostly based on experiences and assumptions of professionals, and not supported by scientific literature and empirical data. Innovative techniques such as eye-tracking and Virtual…
ID
Source
Brief title
Condition
- Neurological disorders of the eye
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Eye movement parameters: fixations (location, duration) and saccades
(direction, amplitude) and task performance (e.g. number of errors, reaction
time) during mobility and search tasks.
Secondary outcome
Neuropsychological paramters, visual parameters, and outcomes of three
questionnaires and semi-structured interviews to evaluate VR + eye-tracking.
Background summary
The largest group of visual disorders after acquired brain injury are
homonymous visual field defects (HVFDs), which refers to visual field deficits
similar for both eyes and contralateral to the brain damage. Homonymous
Hemianopia (HH), in which the left of right half of the visual field is not
perceived, is the most common form of HVFD and occurs in 8-31% of all stroke
patients. HH can have a large influence on daily living, quality of life and
patient*s participation in society. People with HH mainly experience
difficulties in reading, orientation and mobility and they benefit from
training aimed to decrease the impact of the visual field deficit through
optimizing visual scanning. Therefore, it is of utmost importance to inform
patients about how their scanning behaviour relates to difficulties they
experience in daily life and how they can improve their scanning behaviour to
improve these difficulties.
Study objective
Knowledge about which scanning behaviour is optimal, however, is mostly based
on experiences and assumptions of professionals, and not supported by
scientific literature and empirical data. Innovative techniques such as
eye-tracking and Virtual Reality allow us to examine scanning behaviour in a
more standardized manner. In the current project, existing prototypes using
these techniques are being developed into measures that can be used in clinical
practice.
Objective: The aim of this project is to use innovative techniques (i.e.
eye-tracking and Virtual Reality) to examine the relationship between scanning
behaviour and various behaviours (mobility, searching, reading) in patients
with hemianopia, healthy people and healthy people with simulated hemianopia.
This knowlegde can help to improve the rehabilitation for patients with
hemianopia.
Study design
Cross-sectional
Study burden and risks
The effect measures do not include invasive testing. The effect measures have
no adverse consequences for the participant, nor for his/her training at Royal
Dutch Visio and there are no risks involved. Participants will be assessed
using Virtual Reality (VR) and review studies conclude that VR is a safe
rehabilitation training tool, and that studies do not report significant
adverse effects. The assessments can require a certain level of concentration
from which a participant can recover after a short break. The risks of the
study and the burden on the participants are therefore negligible. Participants
know they can refuse or end participation in the study at any time, without any
effect on their individual training at Royal Dutch Visio. Traveling expenses
will be reimbursed.
Grote kruisstraat 2/1
Groningen 9712 TS
NL
Grote kruisstraat 2/1
Groningen 9712 TS
NL
Listed location countries
Age
Inclusion criteria
For patients participating in the test sessions:
- Homonymous visual field defect (at least a quadrantanopia, either right-sided
or left-sided) due to acquired post-chiasmatic brain injury (based on binocular
perimetry)
- At least three months between onset HVFD and the first measurement.
-Written consent including permission to obtain data from the patient file at
Visio.
For all subjects participating in the test sessions:
- Age >=18 years.
- Able to walk at least 50 meters independently or by using a cane/rollator,
without a wheelchair (mobility assessment has to be possible).
- Binocular visual acuity 0.5 or higher using current correction.
- Eye and head mobility undisturbed in all directions.
- MMSE score >= 24.
The inclusion criteria to participate in the training sessions for patients
with HH are:
Age >= 18 years
Homonymous visual field defect.
Exclusion criteria
In the test sessions: a participant meeting any of the following criteria will
be excluded from the study:
- An additional visual field defect in the ipsilesional visual hemi-field.
- Additional visual disturbances (e.g. impaired contrast sensitivity, diplopia,
oscillopsia, metamorphopsia).
- No clear neurological cause of HVFD.
- An indication of severe higher order visual perception disorders, such as
visual agnosia, severe unilateral neglect, or Bálint*s Syndrome.
- Severe psychiatric, cognitive or visual perception disorders.
- Misuse of drugs/alcohol/medication.
- Severe hearing impairment: hearing aids allowed (verbal communication should
be possible).
- Problems with balance or orientation impairing mobility.
- Impairments in understanding or communicating Dutch (spoken) language.
There are no exclusion criteria for patients with HH participating in the
training sessions.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL72491.042.20 |