ABCD-study Phase 7: follow-up measurements at age 19-20 years*

The ABCD -Amsterdam Born Children and their Development-studyis a longitudinal
multi-ethnic birth cohort examining the association between maternal lifestyle,
medical, psychosocial and environmental conditions during pregnancy and
children's health at birth as well as in later life. Specific attention is paid
to ethnic and socioeconomic disparities in child health and development. The
ABCD-study was established in 2003 to increase our knowledge in health
inequalities and related determinants from the earliest age onwards. After
years of extensive data collection, the children participating in the
.ABCD-study are now young adults as they reached the age of 19/20 years. The
last major data collection period was at the age of 11/12 years. To continue
our study, we wish to collect data on physical measurements including
anthropometry, cardiovascular function and metabolic profile. The age of 19/20
years is an important development stage because they are through puberty and
reached young adulthood.

Objectives of phase 7 of the ABCD-study are:
(i) to follow-up on growth trajectories during childhood/adolescence and
identify lifestyle and environmental factors that influence these
trajectories;
(ii) to follow-up on cardiometabolic health during childhood/adolescence and
identify lifestyle and environmental factors that influence this;
(iii) to follow-up on psychosocial health during childhood and identify
lifestyle and environmental factors that influence this;
(iv) to follow-up on cognitive development during childhood and Identify
lifestyle and environmental factors that influence this;
(v) to identity ethnic and socioeconomic differences in the above stated
associations.

The .ABCD-study is a multi-ethnic prospective birth cohort study.

The current study is an observational study and therefore no adverse/serious
adverse events are expected. There is no direct benefit of this study to the
participants. The participants will participate in a health check-up where
blood samples will be collected. Other tests will be non-invasive, including
measurements of anthropometry and cardiovascular function. Moreover during one
week physical activity and sleep patterns will be monitored with an
accelerometer. The risks involved in these measurements are negligible and the
burden is minimal. The measurements were conducted when the children were 5/6
and 11/12 years of age. Long-term follow-up and data analysis is only possible
if measurements are repeated during childhood in a standardised way.