To evaluate existing an currently practiced methods for assessing ocular surface characteristics of DED in order to evaluate their characteristics and comparability.
ID
Source
Brief title
Condition
- Ocular infections, irritations and inflammations
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Tear osmolarity values and tear film characteristics of DED and scoring of a
questionnaire for DED.
Secondary outcome
Correlation between tear osmolarity, tear film characteristics and DED scoring
via questionnaire.
Background summary
Dry eye disease (DED) is defined as a multifactorial disorder of the ocular
surface characterized by a loss of homeostasis of the tear film. This results
in ocular symptoms such as discomfort, sensations of grittiness or pain, and
visual disturbance. DED is the most common reason for seeking medical ocular
care and has a growing prevalence as the global population ages. Historically
there has been a lack of a standardized definition and classification system
for DED. The international report on DED by the Tear film and Ocular surface
Society (TFOS) has advised which parameters should be assessed for diagnosing
DED. There exist multiple methods to assess these parameters and newer methods
are being developed. However, no advice is given on which method is preferred.
Study objective
To evaluate existing an currently practiced methods for assessing ocular
surface characteristics of DED in order to evaluate their characteristics and
comparability.
Study design
Single-center prospective observational study
Study burden and risks
No risks are associated with participation
Meibergdreef 9
Amsterdam 1105 AZ
NL
Meibergdreef 9
Amsterdam 1105 AZ
NL
Listed location countries
Age
Inclusion criteria
- 18 years of age or older
- capable of giving informed consent
- Able to undergo visual acuity measurements, slit lamp examination, Schirmer
II test and to complete a Dutch questionnaire
- Able to undergo measurements with the I-Pen and IDRA devices
Exclusion criteria
- Ophthalmological comorbidities which affect the ocular surface
- Comorbidities with possible ophthalmological consequence
- Previous diagnosis of DED, as diagnosed by a professional clinician
- History of ophthalmological surgical interventions
- Usage of lubricating eye drops or topical drugs for the eye in the last 30
days
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
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In other registers
| Register | ID |
|---|---|
| CCMO | NL82559.018.22 |