The primary aim of this study is to determine the incidence and the degree of retropatellar chondropathy 10 years after a TTT in patients with anterior knee pain without patellar instability. The secondary aim is to evaluate the long-term patient…
ID
Source
Brief title
Condition
- Joint disorders
- Bone and joint therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Degree of retropatellar chondropathy as classified by the Modified Outerbridge
Classification using the MRI-scan of the involved knee
Secondary outcome
Patella height which is determined using standard routine X-ray examination,
and scores on three PROMs: the Knee Injury and Osteoarthritis Outcome Score
(KOOS), the Kujala, and the visual analogue scale (VAS) for pain.
Background summary
Anterior knee pain is a common complaint, especially in younger and active
adults. An obvious source for anterior knee pain is patellar maltracking, which
is often associated with patella alta (a high-riding patella). Due to
maltracking, the cartilage of the patella can face a greater amount of
pressure, which can cause cartilage damage. When conservative treatment fails,
a surgical intervention can be considered. One of the surgical options is
performing a tibial tubercle transfer (TTT), where the patella is being
distalized and medialized. As a result, the improvement in patellar tracking
will reduce the pressure on the retropatellar cartilage. The TTT has been
proven effective in patients with patellar instability but less is known about
patients without instability. Specifically, whether these patients face a
higher risk of developing retropatellar cartilage damage (*retropatellar
chondropathy*) due to this intervention is currently unknown.
Study objective
The primary aim of this study is to determine the incidence and the degree of
retropatellar chondropathy 10 years after a TTT in patients with anterior knee
pain without patellar instability. The secondary aim is to evaluate the
long-term patient reported outcomes (PROMs) 10 years after a TTT in patients
with anterior knee pain without patellar instability.
Study design
This is a 10-year follow-up of a prospective cohort.
Study burden and risks
Patients included in the study will be asked to fill out few PROMs. This will
cost no more than 15 minutes in total. In addition, patients will have one MRI
scan and standard routine radiological assessment of the involved knee
performed. The study will not provide personal benefits to the participating
patients, but future patients may benefit from the results of the study
performed. Ultimately, this study will gain more insight in the long-term
effects after a TTT.
Wilhelminalaan 12
ALKMAAR 1815 JD
NL
Wilhelminalaan 12
ALKMAAR 1815 JD
NL
Listed location countries
Age
Inclusion criteria
Age between 18 and 80 years
Participated in an earlier cohort study
Underwent a tibial tubercle transposition between 2012 and 2015
Preoperative MRI available
Exclusion criteria
No preoperative MRI is available
Patellar-related surgery after the initial surgery
Female patients that are (expecting to be) pregnant
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| ClinicalTrials.gov | NCT05629754 |
| CCMO | NL82613.029.22 |