The objective of the study is to establish a data infrastructure to investigate the degree in which current and previous generations of young-old are characterised by healthy and successful ageing.
ID
Source
Brief title
Condition
- Other condition
- Age related factors
Synonym
Health condition
dagelijks functioneren, algemene gezondheid en welbevinden, chronische ziekten
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main parameters include objective and subjective indicators of physical,
emotional, social and cognitive functioning and care use. Indicators include
functional limitations, performance indicators, bloodmarkers (among others
glucose and vitamin D), depressive symptoms, social network size and received
social support, loneliness, frailty and general cognitive functioning.
Secondary outcome
A broad range of parameters will be included in the data collection. These can
be both endpoints of specific studies or be investigated as confounders or
mediators. An exhaustive list of items that are part of the data collection can
be found in Huisman et al (2011), attached.
A new element in this data collection is an odour test for early identification
of Parkinsonism. Respondents will be asked to identify a series of odours from
a booklet containing surfaces with sample odours, using a multiple choice
format.
In a selection of respondents, in-depth interviews shall be conducted on the
topic of people's living environment. Participants are asked to take
photographs of their living environment as input for the interview.
During the follow-up measurement of 2018/2019, a week calendar shall be left at
the home of a selection of respondents. Respondents are asked to indicate the
degree of pain, sleep, appetite, social contacts they experience and their
mood, for a week. This week calendar shall be administered among respondents of
the LASA Veranderingsstudie (registratienummer 2016/301), a LASA ancillary
study, who have filled out the calendar on previous occasions.
Interim questionnaires include the Tilburg Frailty Indicator questionnaire to
help monitor frailty.
Background summary
Important cultural, economic and social shifts in the late twentieth century
created the Third Age, a phase of life in which people are supposed to enter
old age with the prospect of spending a decade or more free from social
obligations in relatively good health and wealth. The question is to what
extent this prospect applies to all subgroups within the Dutch young-old
population.
Study objective
The objective of the study is to establish a data infrastructure to investigate
the degree in which current and previous generations of young-old are
characterised by healthy and successful ageing.
Study design
Baseline data collection among an additional cohort of young-old respondents,
incorporated within a cohort-sequential longitudinal study of ageing; the
Longitudinal Aging Study Amsterdam (LASA). In-depth interviews shall be
conducted in a small selection of respondents. During follow-up measurements,
participants shall be combined with participants from the existing LASA
infrastructure, so that all respondents receive the same measurements and they
can be compared on important outcomes. In-between regular follow-up
measurements, small-scale questionnaires are administered that focus on a
specific topic.
Study burden and risks
The data collection encompasses a main face-to-face interview and a medical
face-to-face interview, consisting of validated questionnaires and including
among others performance tests and cognitive tests, a self-administered
questionnaire and blood collection. The main and medical interviews will be
conducted separately, on average six weeks apart from one another. The main
interview takes about 1,5 hours, the medical interview 1 hour. The
self-administered questionnaires are left behind by the interviewers conducting
the face-to-face interview and are picked up by the medical interviewers, or
are sent back via mail by the respondents. Interviews take place at the
respondents home address.
Blood will be collected after the medical interview took place. A total of 35ml
blood will be collected. In a selection of respondents, in-depth interviews
shall be conducted on the topic of people's living environment. Participants
are asked to take photographs of their living environment as input for the
interview. The interview takes about 1,5 hours.
We consider the most burdensome aspects of the data collection: a) the general
cognitive functioning, because these may be confronting to respondents, b) the
performance tests, where respondents are asked to walk for a short distance as
fast as possible and are asked to stand up from a chair, and c) The spirometry
measurement, where respondents are asked to forcefully exhale several times.
All data collection is completely observational. The blood collection is the
only invasive element of the study, consisting of one venopuncture in the arm.
In general the risks associated with participation in the study will be
negligible, but for frail older adults the data collection might be more
burdensome. To avoid the burden of a full data collection in these respondents,
we offer as alternatives to participate in a shortened interview that is
administered via telephone, which is less burdensome to respondents, to have a
proxy give the interview for them, or not to participate this time but
retaining their data in our files for future approach. It should be noted that
in this relatively young age group, very few respondents should be expected to
be so frail that the data collection is too burdensome.
There are no specific therapeutic benefits of participation in this study, but
participation may be beneficial to participants because it may be satisfactory
to contribute to a study of relevance to society. Moreover, in case of clearly
deviant values on physical tests (e.g. high blood pressure), this will be
communicated to the general practitioner of the respondent.
The population base consists of young-old adults aged 55-64 years. We aim for a
representative sample, therefore, it is important that people of all abilities
are included. We train our interviewers to be sensitive to respondents* needs
and abilities. In the past 20 years of working with older respondents of all
abilities, we have accumulated great expertise in this respect.
De Boelelaan 1089a
Amsterdam 1081 HV
NL
De Boelelaan 1089a
Amsterdam 1081 HV
NL
Listed location countries
Age
Inclusion criteria
Ages 55-64 years. The study uses a random sample from the Dutch population
registries of 9 municipalities across The Netherlands (the same municipalities
as in 1992 and 2002). In addition, the study uses a random sample of Turkish
and Moroccan migrants of the same age from 13 large and middle-sized cities in
the Netherlands.
Exclusion criteria
Ages other than 55-64 years.
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL41346.029.12 |