The objective of the study is to explore potential beneficial effects of improvisation-based musical training: 1) on speech-on-speech perception and music appreciation in CI users, 2) on HR-QoL-related aspects as well as to explore other nuances in…
ID
Source
Brief title
Condition
- Hearing disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary parameters are the difference between music intervention and
control groups in the baseline-to-endpoint change for speech-on-speech accuracy
and music appreciation ratings.
Secondary outcome
The secondary parameters are the difference between music intervention and
control groups in the baseline-to-endpoint change for other nuanced aspects of
speech- and music perception and HR-QoL questionnaires.
Background summary
A cochlear implant (CI) provides hearing via electric stimulation of the
auditory nerve for people with severe hearing loss to deafness. Yet even with
CIs, this population experiences difficulties in both speech and music
perception. Previous research implies that musical training can benefit
perception of not only music, but also of speech*although this is not
consistently shown, or shown often with small effect sizes. A recent
improvisation-based musical training method, Guided AudioMotor Exploration
(GAME), has shown great potential for more robust improvement in functional MRI
studies in normal-hearing populations. We investigate whether our GAME training
may improve speech and music perception, with a primary focus on two particular
challenges for CI users: speech perception in cocktail party (speech-on-speech)
settings and music appreciation. Another reported benefit of musical training*
or music making*is an accompanying sense of social belonging and improved
quality of life. Considering that CI users often experience a sense of social
isolation, we also wish to explore the impact on health-related quality of life
(HR-QoL) from our music intervention. To assess the impact of our music
intervention, two control groups will be established: One will follow Minecraft
serious gaming lessons (with the same lesson-taking format as the music
intervention) to control for potential influences solely due to increased
social activity and communication, and one will do nothing during the same time
period to control for repeated testing effects.
Study objective
The objective of the study is to explore potential beneficial effects of
improvisation-based musical training: 1) on speech-on-speech perception and
music appreciation in CI users, 2) on HR-QoL-related aspects as well as to
explore other nuances in speech and music perception. The ultimate goal is to
explore and fine-tune training approaches to meet the clinical need for
improved speech and music perception in CI users.
Study design
The intervention study will be a randomized controlled trial with three arms.
Intervention
CI users will be randomized across three 6-month treatments: (1)
improvisation-based piano lessons (music intervention), (2) Minecraft serious
gaming lessons (control intervention), and (3) do nothing (do-nothing control).
NH control participants will not receive an intervention.
Study burden and risks
There are no known risks associated with participation in the study. The
participation for NH controls includes one data collection point consisting of
behavioral perception tests, questionnaires, and physiological metrics. The
participation for CI users includes 18 weekly 45-minute lessons (intervention
groups only), and four data collection points (before, during, after,
follow-up) consisting of the same behavioral perception tests, questionnaires,
and physiological metrics as NH controls (with the addition of an HR-QoL
questionnaire). To reduce potential burden due to fatigue, data will be
collected across multiple sessions adjusted to the stamina of each participant.
Benefit may befall CI-user participants in both intervention groups. The
study*s purpose is to investigate if there is a benefit in auditory perceptual
abilities and/or HR-QoL due to musical training. Improved HR-QoL in the social
domain may be experienced by both intervention groups, as they will join a new
social community (Minecraft serious gamers). Further, both intervention groups
will have the chance to gain a new learning experience, and will potentially
acquire new skills (playing piano, playing Minecraft) which may provide them
further benefits beyond the study scope.
Antonius Deusinglaan 1
Groningen 9700 RB
NL
Antonius Deusinglaan 1
Groningen 9700 RB
NL
Listed location countries
Age
Inclusion criteria
Healthy (normal hearing)
- at least 18 years of age
- native Dutch speaker
- has no language impairment or disorder such as dyslexia
- normal visual acuity (after correction)
- is of general sound health
- normal hearing score on a hearing screening
Patient (CI user)
- at least 18 years of age
- native Dutch speaker
- has no language impairment or disorder such as dyslexia
- has normal visual acuity (after correction)
- has general health as it relates to the ability to participate in the trial
- postlingually deafened
- use at least one cochlear implant, for at least one year before starting the
trial
- never learned piano or similar keyboard instrument
- has had no more than three years of musical training
- has had no regular music making or training within three years prior to the
study
- does not have more than basic knowledge of the serious game *Minecraft*
Exclusion criteria
Healthy (normal hearing)
- younger than 18 years of age
- non-native Dutch speaker
- has a language impairment or disorder such as dyslexia
- has poorer-than-normal visual acuity (after correction)
- is not of general sound health
- has poorer-than-normal hearing as determined by a hearing screening
Patient (CI user)
- younger than 18 years of age
- non-native Dutch speaker
- has a language impairment or disorder such as dyslexia
- has poorer-than-normal visual acuity (after correction)
- has poor general health that impedes the ability to participate in the trial
- prelingually deafened
- received a CI less than one year before the start of the trial
- has already learned a keyboard instrument such as piano
- has had more than three years of musical training
- has had no regular music making or training within three years prior to the
study
- has more than basic knowledge of the serious game *Minecraft*
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL74624.042.20 |