To determine B-cel en T-cel immunity im COVID-19 patients
ID
Source
Brief title
Condition
- Viral infectious disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
To determine both T- and B-cell responses in COVID-19 patients.
Secondary outcome
• To determine the capability of the SARS-CoV-2 ELISpot to detect patients with
a wide range of clinical manifestations with COVID-19
• To determine the dynamics in T-cell and B-cell response in time in COVID-19
patients
• To determine differences in immune responses in severe, moderate and mild
disease
• To relate lineage strain diversity to disease and immune response
• To determine biomarkers linked to development of severe, moderate or mild
disease
• To determine factors for (the development) of immunity to COVID-19
Background summary
Little is known about the development of immunity after COVID-19 infection
Study objective
To determine B-cel en T-cel immunity im COVID-19 patients
Study design
Observational study to determine B- and T-cel responsen against SARS-CoV-2
Study burden and risks
None besides the risc of venapunction
Bosboomstraat 1
Utrecht 3582KE
NL
Bosboomstraat 1
Utrecht 3582KE
NL
Listed location countries
Age
Inclusion criteria
Before and after COVID-19 vaccination
Exclusion criteria
< 18 years old
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| EudraCT | EUCTR2021-001202-30-NL |
| CCMO | NL73618.100.21 |