To assess the efficacy of pre-sleep protein feeding strategies to effectively increase daily protein and energy intake during hospitalization
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
to assess the efficacy of pre-sleep protein feeding strategies to effectively increase daily protein and energy intake during hospitalization
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
total protein intake (g, g·kg body mass-1·day-1) during hospitalization
Secondary outcome
(total) energy intake (kJ), protein distribution, hunger, habitual food intake,
physical activity, grip strength.
Background summary
Hospitalization is generally accompanied by substantial changes in food intake.
Low levels of energy and protein intake results in accelerated loss of lean
body mass and muscle strength. Various strategies can be applied to increase
protein intake during hospitalization, such as providing more protein-rich
foods, fortifying meals and/or food products, supplementation with oral
nutritional supplements (ONS), and/or providing well-timed snacks. The
pre-sleep moment has emerged as a novel window of opportunity to increase daily
protein intake. However, it remains to be established whether pre-sleep protein
feeding represents an effective strategy to increase overall daily protein
intake during hospitalization.
Study objective
To assess the efficacy of pre-sleep protein feeding strategies to effectively
increase daily protein and energy intake during hospitalization
Study design
randomized intervention trial
Intervention
Participants will be randomized to the cheese intervention group (CHEESE,
n=50), or the standard care group (CON, n=50). Patients in the CHEESE will
receive 30 g protein prior to sleep. The CON group will receive standard care
and do not receive a pre-sleep snack. Patients in the CHEESE group will receive
the snack every evening during their hospital stay. Total protein intake,
protein distribution, hunger, handgrip strength, habitual food intake, and
physical activity, will be assessed during the hospital stay.
Study burden and risks
The burden and risks involved in participating in this trial are small. A
benefit is that when patients are randomized to one of the intervention groups,
they will receive a pre-sleep snack. A potential burden can be that a research
will provide them with a hunger questionnaire every morning before breakfast.
Patients will not be restricted to consume snacks and drinks during their
hospital stay
Univerisiteitssingel 50
Maastricht 6229 ER
NL
Univerisiteitssingel 50
Maastricht 6229 ER
NL
Listed location countries
Age
Inclusion criteria
1) Admitted to MUMC+
2) 18-90 y
3) Expected hospital stay at least 2 days
Exclusion criteria
1) Receiving enteral nutrition
2) Receiving parenteral nutrition
3) Dislike cheese
4) Use of MAO-inhibitors
5) Low sodium diet
6) *NPO* (nil per os) policy
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL71830.068.19 |
| Other | Protocol will be registered at NTR after approval by METC |