Generation R is a population based prospective cohort study. The specific aims of the study are:1) To describe normal and abnormal growth, development and health from early fetal life until young adulthood in a multi-ethnic population;2) To identify…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Observationele cohortstudie die zich richt op groei, ontwikkeling en gezondheid vanaf het vroege foetale leven tot de jong volwassenheid. Er wordt een breed scala aan factoren en uitkomsten bestudeerd.
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The study focuses on six areas of research: (1) maternal health; (2) growth and
physical development; (3) behavioural and cognitive development;
(4) respiratory health and allergies; (5) diseases in childhood; and (6) health
and healthcare for children and their parents. In Generation R - Focus at
Teenagers several measurements are performed:
- Dual Energy X Absorptiometry (DXA) measurements
- ECG measurements;
- Ultrasound measurements;
- EEG measurements;
- Endothelial function measurements;
- Eye-tracking measurements;
- Behavior and cognition research;
- Hearing measurements;
- Face and jaw development;
- Skin measurements;
- Biological samples;
- Physical examination;
- Pulmonary examination;
- Gait analyses;
- Mechanography research;
- Collection of medical information;
- MRI scanning;
- Ophthalmologic research;
- Peripheral Quantitative Computed Tomography (pQCT);
- Collection of school information;
- Sleep/actigraphy;
- Spectrophotometry;
- Muscle strength;
- Questionnaires.
Secondary outcome
NA
Background summary
Generation R studies growth, development and health of children from early
pregnancy until adulthood. Ultimately, this research should contribute to the
development of strategies to optimize the health and health care for pregnant
women and their children.
Study objective
Generation R is a population based prospective cohort study. The specific aims
of the study are:
1) To describe normal and abnormal growth, development and health from early
fetal life until young adulthood in a multi-ethnic population;
2) To identify (epi) genetic, biological, social and environmental determinants
of normal and abnormal growth, development and health;
3) To support the development of strategies for prevention and early
identification of groups at risk.
Study design
Generation R is a large-scale multidisciplinary population-based observational
cohort study in Rotterdam
Study burden and risks
Based on the NFU table from the *Monitoringplan t.b.v. WMO-plichtig
investigator initiated onderzoek*, we consider the Generation R Study to be a
study with negligible risk. There are no interventions. There are minimally
invasive procedures, but these only carry a very small risk. The radiation
exposure is low.
Dr Molenwaterplein 50
Rotterdam 3015 GE
NL
Dr Molenwaterplein 50
Rotterdam 3015 GE
NL
Listed location countries
Age
Inclusion criteria
Participation in Generation R Phase 1, Consent for participation in Generation
R Phase 4
Exclusion criteria
Temporary or full withdrawal from participating in the Generation R Study
Death of the child
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL55105.078.15 |