BACKGROUND/OBJECTIVEHospital readmissions are an indicator of quality of care. To assess whether medication reviews with an extensive set of clinicalrules can help to reduce the number of readmissions, we plan to perform a randomised, multicenter,…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
polyfarmaciepatienten met verhoogd risico op heropnames
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
OUTCOME MEASURES
The primary endpoint is the number of readmissions during the year after
admission. An economic evaluation and quality of life
analysis is part of the proposal.
The feasibility of the project is increased as the software is already up and
running, the 3 hospital locations form a closed area
and the research group has a multidisciplinary character including patients.
Based on the calculations we expect to save between ¤26.5 and ¤32.7 M when this
intervention is implemented Nationwide.
Secondary outcome
nvt
Background summary
BACKGROUND/OBJECTIVE
Hospital readmissions are an indicator of quality of care. To assess whether
medication reviews with an extensive set of clinical
rules can help to reduce the number of readmissions, we plan to perform a
randomised, multicenter, transmural trial comparing
medication review with clinical rules versus care as usual. The objective is to
reduce the number of readmissions in older
patients from 20% to 15%. For the Netherlands this may translate into the
prevention of 15.600 hospital readmissions per year
among patients aged 60 years and over (based on pilot study).
Study objective
BACKGROUND/OBJECTIVE
Hospital readmissions are an indicator of quality of care. To assess whether
medication reviews with an extensive set of clinical
rules can help to reduce the number of readmissions, we plan to perform a
randomised, multicenter, transmural trial comparing
medication review with clinical rules versus care as usual. The objective is to
reduce the number of readmissions in older
patients from 20% to 15%. For the Netherlands this may translate into the
prevention of 15.600 hospital readmissions per year
among patients aged 60 years and over (based on pilot study).
Study design
STUDY DESIGN
The study is a prospective multicenter (3 locations) randomised controlled
trial with randomisation at patient level in intervention
and usual care group. The study population consists of patients admitted
unplanned to the hospital and fulfilling the following
criteria: aged 60 years and over, polypharmacy and at least two signals from
the trigger list. In total 1200 patients will be
included per group (power 80%; significance level 5%; ICC 0.05; drop-out 20%).
INTERVENTION
In the intervention group a structured medication review will be performed by a
software program (clinical rule reporter, CRR).
The CRR analyses the patient*s characteristics, medication, medical history and
lab data. The CRR contains more than 500
different clinical rules. The result of the CRR will be presented to
GP/community pharmacist. After discharge the CRR will
analyze the medication of the patient each week.
Study burden and risks
Advices are generated towards the physician/ pharmacist. Its up to them to
follow up the advices or not. The risk for the patient is therefor minimal.
Dr. H. van der Hoffplein 1
Sittard-Geleen 6162 BG
NL
Dr. H. van der Hoffplein 1
Sittard-Geleen 6162 BG
NL
Listed location countries
Age
Inclusion criteria
The study population consists of older people admitted unplanned to the
hospital and fulfilling the following
criteria: 1) aged 60 years and over, 2) ability to give informed consent, 3)
polypharmacy (>5 drugs
chronically), 4) at least two signals from the trigger list as proposed by the
report *Eindrapport
medicatieveiligheid*.
Exclusion criteria
-
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL66886.096.18 |