Collecting blood samples of healthy volunteers (n=650) which can serve as a reference for the Personalized Parkinson Project.
ID
Source
Brief title
Condition
- Movement disorders (incl parkinsonism)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Minimal clinical data extracted from questionnaires and storage of patient
material (cells, serum, plasma, DNA, RNA).
Secondary outcome
-
Background summary
Current biomarkers for Parkinson*s disease are especially valuable for the
differential diagnostics but not for the prediction of the widely varying
differences between patients in prognosis, rate of progression, time to
development of important milestones, or treatment response. The Personalized
Parkinson Project (NL59694.091.16) aims to develop new biomarkers to fill this
gap, but the cohort does not include healthy controls without Parkinson*s,
which hampers the investigation of blood-based biomarkers.
Study objective
Collecting blood samples of healthy volunteers (n=650) which can serve as a
reference for the Personalized Parkinson Project.
Study design
Prospective biobanking program with registry of minimal clinical data and
structured blood sampling at inclusion. Samples will be collected to isolate
cells, plasma, serum, RNA and DNA. Data will be stored in a Castor EDC
database. Blood will be stored in the Radboud UMC biobank.
Study burden and risks
The risk and burden for the biobank participants is negligible (one visit with
blood draw). The venepuncture is associated with a small risk for local
hematoma. There*s no benefit for participants. The biobank can be used to
develop new biomarkers for Parkinson*s disease.
Geert Grooteplein Zuid 20
Nijmegen 6225 GA
NL
Geert Grooteplein Zuid 20
Nijmegen 6225 GA
NL
Listed location countries
Age
Inclusion criteria
- Subject is an adult, at least 18 years of age.
- Subject can read and understand Dutch.
- Subject has completed CMO-approved Informed Consent.
- Subject is willing, competent, and able to comply with all aspects of the
protocol, including biospecimen collections.
Exclusion criteria
- Subject is pregnant or breastfeeding.
- Subject has Parkinson*s disease.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL85147.091.23 |