Evaluation of the Karman Line memory strategy training, a combined computerized and face-to-face compensatory treatment targeting memory complaints after acquired brain injury, using single-case experimental design methodology.

Acquired brain injury (ABI) often results in memory deficits that can have a
great impact on social or vocational functioning of patients. Treatment of
memory dysfunction consists of optimizing memory performance by using
effective compensation strategies. Several effective memory-strategy programs
have been developed. These often contain labor-intensive treatment-protocols.
For this reason, we developed a blended care training of memory strategies,
which consists of a shortened traditional face-to face treatment in combination
with an innovative Brain Game based on compensation strategies. This is a
promising cost-effective intervention that provides the possibility of repeated
practice at home in a safe and imaginative digital environment. Until now,
brain games on restore brain function, of which effects do not generalize to
daily life functioning. Our hypothesis is the compensation brain game will
promote generalization, also after rehabilitation ends.

The primary objective is the evaluation of the potential positive effect of a
compensatory memory strategy game on effective coping with memory problems and
reducing subjective memory failures in ABI patients with memory deficits in the
chronic phase of acquired brain injury (>3 months after injury).

The study will be a multiple-baseline across individuals single-case
experimental design (SCED).

The memory strategy training consists of six weekly treatment sessions under
guidance of a therapist. The protocol is a shortened version of an existing
memory strategy training. In the sessions, patients get information about
memory and memory strategies and learn to apply those to their personal
treatment goals. In between the sessions, the participant will work on personal
memory goals and practice the strategies by playing the corresponding memory
game at home.

The burden in the study consists of participating in repeated measurements,
therapy sessions, and homework assignments. All tests and methods that are used
are non-invasive and not stressful for the patient. All tests and tasks will be
based on widely-used validated and reliable paper-pencil or computer tasks.
Treatment is non-invasive and scarcely stressful: a therapist will always be
present and assess the patients burden and eventually take appropriate measures
such as inserting a resting break.