The prognostic accuracy of combining these four criteria to predict the later development of personality disorders (with/without psychosocial breakdown) is investigated in a longitudinal study. From this, a selection of items with the strongest…
ID
Source
Brief title
Condition
- Personality disorders and disturbances in behaviour
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
At baseline, the various instruments belonging to the four appraisals are
administered: interpersonal trauma (JTV), personality functioning (STiP-5.1 KV
+ PV, LoPF-Q), social support system (QSS-A) and onset characteristics of PD,
both symptom-based (SCID-5-P, BPFSC) and trait-based (DIPSI-BPS traits). We
also conduct baseline measurement of psychosocial functioning (KidScreen, SMA,
Social Support, school functioning and Promis Peer). Here we choose a
multi-method and multi-informant approach, as reflected in a set of instruments
with both self-reporting and reporting by others. In follow-up, the same
instruments will be administered, with the exception of the trauma
questionnaire. However, a modified survey of recent life events will be added.
A detailed description of all instruments is attached.
The primary predictable outcome is the presence or absence of a personality
disorder after 36 months.
Secondary outcome
See above
Background summary
Optimal indication for indicated prevention requires that the onset of a mental
disorder can be be predicted and is especially relevant for conditions with
progressive social breakdown. This study investigates the prognostic value of a
multi-factorial risk test for personality disorders, based on the evaluation of
four ultra-high-risk criteria: interpersonal trauma, current personality
functioning, quality of social support system and subclinical features of
borderline personality pathology.
Study objective
The prognostic accuracy of combining these four criteria to predict the later
development of personality disorders (with/without psychosocial breakdown) is
investigated in a longitudinal study. From this, a selection of items with the
strongest prognostic value will be derived (screener).
Study design
This study uses a prospective, longitudinal design in which four pre-identified
UHR criteria for PS are assessed at baseline in young adolescents (11-14 years)
from both a risk and a cohort sample. These adolescents are then followed up
for 3 years, with follow-up measurements at 1, 2 and 3 years assessing which
adolescents are developing or have developed a PS and which adolescents with PD
are (or are beginning to) socially disengaged, as well as which adolescents are
resuming a normative developmental trajectory (multifinality). The prognostic
accuracy of the baseline test based on four UHR criteria for developing a
personality disorder (with/without social dropout) is investigated.
Study burden and risks
There are four measurement moments for both parents and children. At each
measurement moment there are interviews and questionnaires. For children, the
workload is estimated at 90 minutes per assessment, for parents at 60 minutes
at the first assessment and 45 minutes at follow-up assessments. Interviews and
questionnaires deal with personality and psychological symptoms. The
instruments have all been used before for studies in these target groups.
Warandelaan 2
Tilburg 5037 AB
NL
Warandelaan 2
Tilburg 5037 AB
NL
Listed location countries
Age
Inclusion criteria
For this study, children (and their parent) between 11 and 14 years will be
recruited from risk samples and cohort samples.The risk samples will be
recruited in the Netherlands (within the Viersprong and a number of foster care
services) on the one hand, and within Flemish General Paediatrics (AP) and
Child and Adolescent Psychiatry services on the other. Within de Viersprong, we
recruit in two treatment programmes: MST-CAN (children with documented
intrafamilial experiences of abuse or severe neglect) and MBT-early (children
with incipient features of Borderline PD). From existing research
collaborations between Ghent University and a number of Flemish AP and KJP
services, additional young teenagers with incipient characteristics of
Borderline PD will be recruited. A third risk sample will be recruited in
collaboration with the foster care services Vigere and Sterkhuis. The first and
third high-risk samples are recruited because, by definition, there are
interpersonal traumatic experiences in childhood, which is seen as a major risk
factor for the development of personality problems. The second risk sample is
recruited because, by definition, there are (incipient) characteristics of BPD,
which is a demonstrated risk factor for the development of PD in late
adolescence and young adulthood as well as for social, community and health
problems. The cohort sample is a 'convenience' sample that we will include
mainly to recruit children with a presumed low-risk on the various risk
factors. These participants will be recruited through schools. Through quota
sampling, predetermined quotas for age and socio-economic status will be set to
ensure representativeness of the sample. Participants in each sample will
always be the children/young people and one of the (foster) parents or other
caregiver who assumes a close parenting role.
Exclusion criteria
Inability to participate in interviews or questionnaires due to insufficient
command of language, intelligence or for other reasons
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL87456.028.24 |