Patients with COPD have worse cognitive functioning compared to healthy controls. This may influence health status, daily functioning and the outcome of pulmonary rehabilitation in these patients.
ID
Bron
Verkorte titel
Aandoening
* Chronic obstructive pulmonary disease
* Chronisch obstructief longlijden
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Neuropsychological functioning.
Achtergrond van het onderzoek
Patients with Chronic Obstructive Pulmonary Disease (COPD) may experience dyspnoea, fatigue and problems in daily functioning, despite optimal pharmacological treatment. It is important that patients follow a number of precepts in order to minimize the consequences of the illness. Before a patient is willing to follow the precepts, a patient needs to experience that the new behaviour yields more advantages, compared to the old behaviour. Patients need specific cognitive abilities in order to make a considered choice. Previous research suggests that the cognitive functions of COPD patients may be impaired. However, results of previous research are disputable. To date, remains unclear which clinical characteristics are related to cognitive functioning in COPD patients and whether and to what extent cognitive functioning is related to daily functioning, health status and the outcome of pulmonary rehabilitation.
Doel van het onderzoek
Patients with COPD have worse cognitive functioning compared to healthy controls. This may influence health status, daily functioning and the outcome of pulmonary rehabilitation in these patients.
Onderzoeksopzet
Before and after an 8-14 week pulmonary rehabilitation program.
Onderzoeksproduct en/of interventie
n/a
Algemeen / deelnemers
Fiona Cleutjens
Hoorn 6085 NM
The Netherlands
+31 (0)475 587 606
fionacleutjens@ciro-horn.nl
Wetenschappers
Fiona Cleutjens
Hoorn 6085 NM
The Netherlands
+31 (0)475 587 606
fionacleutjens@ciro-horn.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Patients:
* Diagnosis: COPD according to the GOLD definition.
Matched control group:
* Partner, brother or sister of an included patient.
* Smoking status comparable with smoking status from included patient.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Patients:
* Patient is not clinically stable during 4 weeks preceding enrolment.
* Previous diagnosis of dementia.
* Patient does not speak Dutch well enough to participate.
Brain MRI patient group:
* The patient has a pacemaker, cochlear implant, neurostimulator or other electronic implants, surgery with metal implants, or ever had a metal splinter in the eye.
* The patient suffers from claustrophobia.
Matched control group:
* Diagnoses of COPD or Asthma.
* Previous diagnosis of dementia.
* Participant does not speak Dutch well
enough to participate.
* Age of the matched control differ more than 10 years from the age of the patient for who he/she was matched.
* Level of education of the matched control differs more than 1 level from the level of education for who he/she was matched (according to the scoring system of the CBS).
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4064 |
| NTR-old | NTR4215 |
| CCMO | NL45127.068.13 |
| ISRCTN | ISRCTN wordt niet meer aangeleverd. |
| OMON | NL-OMON40538 |