Insomnia patients form a heterogeneous group, each phenotypes of insomnia will show different therapeutic demands.
ID
Bron
Verkorte titel
Aandoening
Insomnia, phenotypes
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The change from baseline to post-treatment on a composite score that summarizes subjectie insomnia complaints, queried daily through an internet diary.
Achtergrond van het onderzoek
Insomnia is a condition that affects about 10% of the Western population. At present, the most common solution provided by primary care givers is pharmacological treatment. However, pharmacological treatments have a high prevalence of negative side effects. Two more recently developed treatments are chronobiological treatment (CT) and cognitive behavioral therapy (CBT). They appear safer and have more sustained effects. A problem facing implementation of CBT-I is that there are hardly any skilled therapists. Web-based CBT-I may this alleviate this problem.
A second opportunity for optimization of treatment is based on the contention that the people with insomnia most likely represent a heterogeneous mix of different subtypes, with different underlying causes and expected treatment response. This is the first step in the development of a protocol for individualized optimal treatment for specific phenotypes of insomnia, where each phenotype may show different CT and CBT-I demands.
In a systematic way the effectiveness of CT, CBT-I and their combination will be evaluated for the different phenotypes.
Doel van het onderzoek
Insomnia patients form a heterogeneous group, each phenotypes of insomnia will show different therapeutic demands.
Onderzoeksopzet
Baseline, 5 weeks and 10 weeks.
Onderzoeksproduct en/of interventie
Web-based cognitive behavioral therapy for insomnia (CBT-I)
3 forms of chronobiological therapy (CT):
-Bright light therapy
-Thermoregulatory therapy
-Physical activity
Combinations of CBT-I and CTs.
Publiek
Meibergdreef 47
Kim Dekker
Amsterdam 1105 BA
The Netherlands
020-5665492
k.dekker@nin.knaw.nl
Wetenschappelijk
Meibergdreef 47
Kim Dekker
Amsterdam 1105 BA
The Netherlands
020-5665492
k.dekker@nin.knaw.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1) 18-70 years of age;
2) Insomnia.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1) Other neurological or psychiatric disorders
eye diseases;
2) Cardiovascular or movement disorders;
3) Shiftworkers;
4) Use of sleep medication 3 months prior to inclusion;
5) Habitual level of light intake, physical activity or bathing habits equal to therapy.
Opzet
Deelname
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