To investigate differences in clinical outcome between patients with lytic spondylolisthesis and residual hernia surgery pain undergoing minimal invasive spinal fusion surgery. Beside this clinical outcome we investigate the radiological outcome of…
ID
Bron
Verkorte titel
Aandoening
- Pees-, ligament- en kraakbeenaandoeningen
Synoniemen aandoening
Betreft onderzoek met
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Is the outcome of patients undergoing 1- or 2-level posterior lumbar interbody
fusion in combination with minimally invasive pedicle screw placement
(MIP-PLIF technique) the same for patients who had residual hernia surgery pain
as for patients with lytic spondylolisthesis?
Secundaire uitkomstmaten
Does significant subsidence of the cage occur two years after surgery in these
80 patients? If there is significant subsidence, is there a significant
difference between the groups?
Achtergrond van het onderzoek
Minimally invasive lumbar fusion surgery is in his infancy. Magerl first
reported the use of percutaneous pedicle screws for spinal fusion in 1982.
Foley et al subsequently advanced the design of percutaneous pedicle screws,
combined with the tubular retractor system. This led to the development of
minimally invasive percutaneous posterior lumbar interbody fusion (MIP-PLIF).
The first MIP-PLIF using the Sextant system (Medtronic) was performed in 2001.
The first results of this new technique are promising and in our hospital we
have performed lumbar fusion with the Sextant system in over 300 patients with
lytic spondylolisthesis and patients with recurrent radiculopathy after hernia
surgery. Our experience is that patients with a lytic spondylolisthesis
undergoing minimally invasive interbody fusion have a better outcome than
patients with recurrent radiculopathy after hernia surgery. To our knowledge
there is no study comparing the outcome of lumbar fusion surgery in these
patient groups.
Doel van het onderzoek
To investigate differences in clinical outcome between patients with lytic
spondylolisthesis and residual hernia surgery pain undergoing minimal invasive
spinal fusion surgery. Beside this clinical outcome we investigate the
radiological outcome of the lumbar fusions.
Onderzoeksopzet
Retrospective study with prospective follow-up. Two cohorts of an equal number
of 40 patients. One cohort with diagnosis lytic spondylolisthesis and one with
diagnosis recurrent radiculopathy after hernia surgery. All 80 patients
underwent 1-level or 2-level lumbar spine fusion in our hospital between 2002
and 2010, using the MIP-PLIF technique (Sextant system, Medtronic). The cohorts
will be matched for age, gender and follow-up time. Data will be collected
after a minimal follow-up time of two years after surgery. Enrolment criteria
included available demographic, surgical and clinical outcome data.
Inschatting van belasting en risico
een enkele rontgenfoto (X-LWK lateraal)
Algemeen / deelnemers
Hilvarenbeekseweg 60
5022 GC Tilburg
NL
Wetenschappers
Hilvarenbeekseweg 60
5022 GC Tilburg
NL
Landen waar het onderzoek wordt uitgevoerd
Leeftijd
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Volwassenen (>18 jaar)
Patienten die een lumbale spondylodese op 1- of 2-niveaus hebben ondergaan met de nieuwe sextant techniek (verricht in St Elisabeth ziekenhuis tussen 2002 en 2010)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Geen eerdere spondylodese operatie ondergaan voor de spondylodese middels sextant techniek
Leeftijd <18jaar
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| CCMO | NL38113.008.11 |