In this project we hypothesize that recurrent pregnancy loss is an issue stemming from both the female and the male.
ID
Bron
Verkorte titel
Aandoening
Recurrent Pregnancy Loss
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Case-control study: paternal age
Cohort study: development of live birth within 5 years after initial consultation
Achtergrond van het onderzoek
In this project we hypothesize that recurrent pregnancy loss is an issue stemming from both the female and the male. The overall aims are to identify paternal factors associated with RPL (A) and to assess the predictive value of these factors on the outcome of a next pregnancy in patients with RPL (B).
Doel van het onderzoek
In this project we hypothesize that recurrent pregnancy loss is an issue stemming from both the female and the male.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
None - observational
Algemeen / deelnemers
Wetenschappers
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Cases: Unexplained recurrent pregnancy loss (according to ESHRE guideline RPL 2017)
Controls: ≤ 1 spontaneous miscarriage, proven fertility (i.e. pregnant at inclusion or previously experienced pregnancy in same relationship)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Cases: 1) known causes for RPL (parental chromosomal chromosomal abnormalities, uterine anomalies, acquired or hereditary thrombophilia, hyperhomocystenaemia and untreated or instable endocrine disease); 2) mentally or legally incapibility of either male or female; 3) treatment with oocyte, embryo or spermatozoa donation; 4) loss of < 2 pregnancies in current relationship
Controls: 1) any known cause for RPL as described above; 2) mentally or legally incapibility of either male or female; 3) treatment with oocyte, embryo or spermatozoa donation
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL7762 |
| Ander register | METC LUMC : P19.014 |