Medial arterial calcification in patients with haemophilia

In hemophilia patients arterial hypertension is more common than in de general population. The cause of this increased prevalence is unknown. Recent studies on atherosclerosis in hemophilia focused on intima lesions. However, arterial calcification may affect the media as well. Medial arterial calcification (MAC) leads to concentric media thickening and stiffening of the arterial wall. Since arterial stiffness is an important contributor to arterial hypertension, MAC and consequently arterial stiffness may be more prevalent in hemophiliacs, and this may explain the high rate of systolic hypertension. MAC can be detected by measurement of the ankle brachial index. There are no reports on MAC in hemophilia.

single visit

Single measurement of ankel brachial index and toe brachial index.