Peri-operative interventions improve fragile patients functional health status, reduce complications and length of stay in hospital after elective surgery.
ID
Bron
Verkorte titel
Aandoening
Fragility, multimorbidity, post-operative complications, preventive and screening intervention
Fragiliteit, multimorbiditeit, postoperatieve complicaties, preventieve en screening interventie
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Length of hospital stay and postoperative complications.
Achtergrond van het onderzoek
Hospital admission can be a major life event for fragile older people, associated with increased morbidity and mortality. Especially, large invasive surgical interventions are in elderly patients increasingly accompanied with complications, delirium, loss of function and mortality. To decease post-surgical complications in fragile older patients indicated for elective surgery a pre-surgical multidisciplinary intervention was designed in order to increase the older patients' physical and mental condition before surgery and to prevent them from complications and loss of indenpendency after surgery. The cost-effectiveness of the intervention is tested in a randomized clinical trial. The control group receives the care as usual. Primary outcome is complications after surgery and length of stay in hospital. Secondary outcome focusses on physical functioning, quality of life, and level of independency. To show effectiveness it was calculated that 40 patients should be included in the intervention arm and 40 in the control-arm.
Doel van het onderzoek
Peri-operative interventions improve fragile patients functional health status, reduce complications and length of stay in hospital after elective surgery.
Onderzoeksopzet
T0 Baseline measurement: Before randomization;
T1 On hospital admission;
T2 Short term measurement: 30 days after the operation;
T3 Long term measurement: 6 months after operation.
Onderzoeksproduct en/of interventie
Peri-operative tailormade intervention aims at:
1. Optimizing physical condition by preoperative functional trainingprogramm by a physiotherapist, 2/3 times a week at the clients home;
2. Preoperative nutritional status assessment and optimalisation by a dietician, counseling once a week;
3. Reducing risk factors for delirium by a geriatric specialist;
4. Prescribing Optimalization Method for optimalization of medication use by a geritric specialist;
5. Organizing postoperative home care.
Minimal duration of the intervention is 3 weeks.
The control group receives care as usual. That means no peri-operative intervention
Algemeen / deelnemers
Wetenschappers
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Fragile, community-dwelling elderly, 70 years and older, who are on a waiting list for abdominal or thoracal surgery.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Endoscopic and gynaecological operations.
Opzet
Deelname
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In overige registers
Register | ID |
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NTR-new | NL2501 |
NTR-old | NTR2618 |
Ander register | ZonMW/NPO : 60-61900-98-280 |
ISRCTN | ISRCTN wordt niet meer aangevraagd. |