De status van het micromilieu van de (schildwacht)klier en tumor bij patiënten met baarmoederhalskanker.

This is an exploratory study to further delineate the microenvironment of the primary tumour and (sentinel) lymph nodes in cervical cancer.All patients diagnosed with cervical carcinoma who will undergo an operation or a lymphadenectomy will be asked to participate in the study. Patients who will undergo a lymphadenectomy will be asked to participate in detecting the SLNs prior to the lymph node dissection by injecting ICG/patent blue in the tumour before the operation starts in the operation room. Patients who will undergo a lymph node debulking in the context of chemoradiotherapy, will be asked permission to obtain a small tumour biopsy.

This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.

- blood will be drawn before surgery and 3 months after surgery

- patients will be asked to give permission to search for sentinel node(s), by injecting patent blue

- patients will be asked to donate 2x 10 ml blood for further analysis (at two different timepoints)