By its pharmalogical action it is likely that aspirin improves ovarian perfusion, uterine perfusion and reduces endometrial restraint on the implanting embryo. Therefore the hypothesis of this study is that the use of low dose aspirin in IVF…
ID
Bron
Verkorte titel
Aandoening
Subfertility
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Ongoing pregnancy rate.
Achtergrond van het onderzoek
A prospective, randomized, double blind, placebo controled trial. Patients under the age of 39 years undergoing regular IVF or ICSI treatment combined with low dose aspirin or placebo.
Doel van het onderzoek
By its pharmalogical action it is likely that aspirin improves ovarian perfusion, uterine perfusion and reduces endometrial restraint on the implanting embryo. Therefore the hypothesis of this study is that the use of low dose aspirin in IVF improves pregnancy rates.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Patients undergo regular IVF/ICSI treatment combined with low dose aspirin or placebo.
Algemeen / deelnemers
P.G.A. Hompes
VU University Medical Center, Department of Reproductive Medicine
De Boelelaan 1117
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4444444
p.hompes@vumc.nl
Wetenschappers
P.G.A. Hompes
VU University Medical Center, Department of Reproductive Medicine
De Boelelaan 1117
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4444444
p.hompes@vumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Patients undergoing IVF or ICSI treatment;
2. Age <39 years;
3. Cycle day 3 FSH < 10 IU/L;
4. No contra indications against the use of low-dose aspirin.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Systemic diseases;
2. Hypertension;
3. Previous allergic reaction to study medication;
4. Previous OHSS;
5. Untreated endocrinopathies;
6. Smoking > 5 cigarettes/day;
7. BMI > 28.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL554 |
| NTR-old | NTR610 |
| Ander register | : N/A |
| ISRCTN | ISRCTN97507474 |