Elderly ICU patients have a lower phase angle due to physiological changes in water-electrolytes balance and reduced caloric intake. We expect to find an association between a low phase angle, ICU length of stay and clinical outcome.
ID
Bron
Verkorte titel
Aandoening
cardiopulmonary surgery, sepsis, pneumonia, malnutrition, electrolyte disturbance
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
- ICU mortality and hospital mortality
Achtergrond van het onderzoek
Rationale: An increasing percentage of patients admitted to the ICU is of elderly age. Aging is associated with physiological of psychosocial changes which increase the risk of malnutrition. Bioelectrical impedance vector analysis (BIVA) and calculation of phase angle (PA) is an simple non-invasive way to measure body composition and considered a useful marker for nutritional status of ICU-patients.
Objective: The aim of this study is to investigate whether phase angle is an independent predictor of clinical outcome in elderly ICU patients. Early detection of malnutrition in elderly could contribute to the dialogue whether an individual patient is fit for ICU treatment.
Study design: Observational retrospective single centre cohort study
Population: Patients aged 80 years or older admitted to the ICU
Primary outcome: ICU/hospital length of stay and ICU/hospital mortality
Doel van het onderzoek
Elderly ICU patients have a lower phase angle due to physiological changes in water-electrolytes balance and reduced caloric intake. We expect to find an association between a low phase angle, ICU length of stay and clinical outcome.
Onderzoeksopzet
- Clinical parameters and blood samples taken on ICU-admission
- Serum phosphate during first 3 days of ICU stay
- ICU discharge
- Hospital discharge
Onderzoeksproduct en/of interventie
Observational study, all clinical parameters and blood samples are collected according to the standard protocol. Based on study findings no extra interventions will be done.
Algemeen / deelnemers
Wetenschappers
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1) Patients aged 80 years or older
2) ICU stay between 1-4-2018 and 1-4-2020
3) Length of stay on ICU at least 6 hours
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1) Re-admission to the ICU
2) Unable to measure phase angle due to neurological, anatomical or skin-related abnormalities of the limbs
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL8823 |
| Ander register | RTPO MCL : nWMO20200043 |